475469-15-9

Basic information

• Product Name: (3-HYDROXYMETHYL-PYRROLIDIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: (3-HYDROXYMETHYL-PYRROLIDIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER;TERT-BUTYL 3-(HYDROXYMETHYL)PYRROLIDIN-3-YLCARBAMATE;Carbamic acid, [3-(hydroxymethyl)-3-pyrrolidinyl]-, 1,1-dimethylethyl ester (9CI);Tert-butyl 3-(hydroxymethyl)pyrrolin-3-ylcarbamate;3-(hydroxymethyl)-3-Boc-amino-pyrrolidin;3-Boc-amino-3-(hydroxymethyl)pyrrolidine;N-(3-HydroxyMethylpyrrolidin-3-yl)carbaMic acid tert-butyl ester;CarbaMic acid, N-[3-(hydroxyMethyl)-3-pyrrolidinyl]-, 1,1-diMethylethyl ester
• CAS NO: 475469-15-9
• Molecular Formula: C₁₀H₂₀N₂O₃
• Molecular Weight: 216.28
• Product Categories: N-BOC
• Mol File: 475469-15-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 346.857 °C at 760 mmHg
• Flash Point: 163.574 °C
• Appearance: /
• Density: 1.123 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.504
• Storage Temp.: Sealed in dry,Store in freezer, under -20°C
• CAS DataBase Reference: (3-HYDROXYMETHYL-PYRROLIDIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (3-HYDROXYMETHYL-PYRROLIDIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER(475469-15-9)
• EPA Substance Registry System: (3-HYDROXYMETHYL-PYRROLIDIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER(475469-15-9)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 475469-15-9(Hazardous Substances Data)

Usage

General Description

"(3-Hydroxymethyl-pyrrolidin-3-yl)-carbamic acid tert-butyl ester" is a complex synthetic compound that belongs to a class of chemical substances known as esters. (3-HYDROXYMETHYL-PYRROLIDIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER is characterized by the presence of a carbamic acid unit (which is a derivative of carbamic acid and carries both carboxylic acid and amine substituents) as well as a pyrrolidine ring, a common feature of many natural products, drugs, and experimental substances. The tert-butyl ester component of the molecule refers to the tertiary butyl group attached to the carbamic acid unit, modifying the molecule’s chemical behavior and properties. Due to its complex structure, this chemical is likely used in advanced organic synthesis, potentially serving a crucial role in the pharmaceutical or chemical industries. However, specific applications vary depending on the context of the compound’s synthesis and the overarching goals of the project or research.

InChI:InChI=1/C10H20N2O3/c1-9(2,3)15-8(14)12-10(7-13)4-5-11-6-10/h11,13H,4-7H2,1-3H3,(H,12,14)

Upstream product

• 475469-14-8 1-benzyl-3-N-tert-butoxycarbonylamino-3-hydroxymethylpyrrolidine 
• 475469-12-6 3-amino-1-benzyl-3-ethoxycarbonylpyrrolidine 
• 145602-87-5 3-amino-1-benzylpyrrolidine-3-carboxylic acid 
• 475469-13-7 3-amino-1-benzyl-3-hydroxymethylpyrrolidine 
• 28863-87-8 7-benzyl-1,3,7-triazaspiro[4.4]nonane-2,4-dione 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1004992-18-0 tert-butyl (R)-1-benzyl-3-(hydroxymethyl)pyrrolidin-3-ylcarbamate 
• 1004992-31-7 benzyl 3-((tert-butoxycarbonyl)amino)-3-(hydroxymethyl)pyrrolidine-1-carboxylate 
• 1613021-46-7 1-(4-fluorophenyl)-N-[(3S)-3-(hydroxymethyl)-1-imidazo[1,2-a]pyrazin-8-yl-pyrrolidin-3-yl]pyrazole-3-carboxamide 
• 1613021-48-9 N-[(3S)-3-(hydroxymethyl)-1-imidazo[1,2-a]pyrazin-8-yl-pyrrolidin-3-yl]-1-phenyl-1,2,4-triazole-3-carboxamide 

Relevant articles and documents

Synthesis and structure-activity relationships of novel 7-substituted 1,4-dihydro-4-oxo-1-(2-thiazolyl)-1,8-naphthyridine-3-carboxylic acids as antitumor agents. Part 1

In an attempt to search for clinically useful antitumor agents, we have discovered that a series of 1,7-disubstituted-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acids possessed moderate cytotoxic activity. We investigated the structure-acti