475571-08-5

Basic information

• Product Name: (S)-2-phenethyl-4-tert-butyloxazoline
• Synonyms: (S)-2-phenethyl-4-tert-butyloxazoline
• CAS NO: 475571-08-5
• Molecular Weight: 231.338
• Mol File: 475571-08-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (S)-2-phenethyl-4-tert-butyloxazoline(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-2-phenethyl-4-tert-butyloxazoline(475571-08-5)
• EPA Substance Registry System: (S)-2-phenethyl-4-tert-butyloxazoline(475571-08-5)

Safety Data

• Hazardous Substances Data: 475571-08-5(Hazardous Substances Data)

Upstream product

• 103-25-3 3-phenylpropanoic acid methyl ester 
• 112245-13-3 (S)-tert-leucinol 
• 501-52-0 3-Phenylpropionic acid 

Relevant articles and documents

CONDENSATION REACTION BY METAL CATALYST

The invention relates to a method for producing an azoline compound represented by the general formula (3): wherein R1 represents an optionally substituted hydrocarbon group, an optionally substituted alkoxy group, an optionally substituted alkoxycarbonyl group, a halogen atom, a substituted amino group, a substituted carbamoyl group or an optionally substituted heterocyclic group; R3, R4, R5 and R6 may be the same or different and each represents a hydrogen atom, an optionally substituted hydrocarbon group, an optionally substituted alkoxy group, an optionally substituted alkoxycarbonyl group, a halogen atom, a substituted amino group, a substituted carbamoyl group or an optionally substituted heterocyclic group; two arbitrary groups selected from R3, R4, R5 and R6 may bond to each other to form a ring; and Z1 represents an oxygen atom, a sulfur atom or a selenium atom; comprising reacting a carboxylic acid or a carboxylic acid derivative represented by the general formula (1): ????????R1CO2R2?????(1) wherein R1 is as defined above; R2 represents a hydrogen atom, an optionally substituted alkyl group or an optionally substituted aryl group; and R1 and R2 may bond to each other to form a ring; with an aminochalcogenide represented by the general formula (2): wherein R3, R4, R5, R6 and Z1 are as defined above; in the presence of a compound containing a group 12 metal element in the periodic table.