475585-19-4

Basic information

• Product Name: 2-methyl-5-{[6-(4-nitrophenyl)furo[2,3-d]pyrimidin-4-yl]amino}phenol
• Synonyms: 2-methyl-5-{[6-(4-nitrophenyl)furo[2,3-d]pyrimidin-4-yl]amino}phenol
• CAS NO: 475585-19-4
• Molecular Weight: 362.345
• Mol File: 475585-19-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-methyl-5-{[6-(4-nitrophenyl)furo[2,3-d]pyrimidin-4-yl]amino}phenol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-5-{[6-(4-nitrophenyl)furo[2,3-d]pyrimidin-4-yl]amino}phenol(475585-19-4)
• EPA Substance Registry System: 2-methyl-5-{[6-(4-nitrophenyl)furo[2,3-d]pyrimidin-4-yl]amino}phenol(475585-19-4)

Safety Data

• Hazardous Substances Data: 475585-19-4(Hazardous Substances Data)

Upstream product

• 475585-16-1 diethyl 2-amino-5-(4-nitrophenyl)furan-3,4-dicarboxylate 
• 475585-14-9 ethyl 4-hydroxy-6-(4-nitrophenyl)furo[2,3-d]pyrimidine-5-carboxylate 
• 475585-13-8 4-hydroxy-6-(4-nitrophenyl)furo[2,3-d]pyrimidine-5-carboxylic acid 
• 475585-12-7 6-(4-nitrophenyl)furo[2,3-d]pyrimidin-4-ol 
• 74476-72-5 ethyl 2-chloro-3-(4-nitrophenyl)-3-oxopropanoate 
• 838-57-3 ethyl 4-nitrobenzoylacetate 
• 2835-95-2 amino-4 hydroxy-2 toluene 
• 475585-11-6 4-chloro-6-(4-nitrophenyl)furo[2,3-d]pyrimidine 

Relevant articles and documents

Furo[2,3-d]pyrimidines and Oxazolo[5,4-d]pyrimidines as Inhibitors of Receptor Tyrosine Kinases (RTK)

Receptor tyrosine kinases such as VEGFR2 (vascular endothelial growth factor receptor 2, KDR) or EGFR (epidermal growth factor receptor) play crucial roles in a variety of diseases, such as cancer. Recently, some pyrrolopyrimidines were shown to be potent