476415-60-8

Basic information

• Product Name: tetrahydro-3-furanylacetonitrile(SALTDATA: FREE)
• Synonyms: tetrahydro-3-furanylacetonitrile(SALTDATA: FREE);2-(tetrahydrofuran-3-yl)acetonitrile;tetrahydro-3-furanylacetonitrile
• CAS NO: 476415-60-8
• Molecular Formula: C6H9NO
• Molecular Weight: 111.14176
• Mol File: 476415-60-8.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 227.4±13.0 °C(Predicted)
• Appearance: /
• Density: 1.003±0.06 g/cm3(Predicted)
• CAS DataBase Reference: tetrahydro-3-furanylacetonitrile(SALTDATA: FREE)(CAS DataBase Reference)
• NIST Chemistry Reference: tetrahydro-3-furanylacetonitrile(SALTDATA: FREE)(476415-60-8)
• EPA Substance Registry System: tetrahydro-3-furanylacetonitrile(SALTDATA: FREE)(476415-60-8)

Safety Data

• Hazardous Substances Data: 476415-60-8(Hazardous Substances Data)

Usage

Description

Tetrahydro-3-furanylacetonitrile (SALTDATA: FREE) is a chemical compound with the molecular formula C6H9NO. It is a nitrile and furan-containing compound with a tetrahydrofuran ring. This colorless liquid at room temperature is known for its distinctive odor and versatile reactivity, making it a valuable building block in organic synthesis and pharmaceutical production.

Uses

Used in Organic Synthesis:
Tetrahydro-3-furanylacetonitrile (SALTDATA: FREE) is used as a key intermediate in the synthesis of various organic compounds due to its functional groups and reactivity.
Used in Pharmaceutical Industry:
Tetrahydro-3-furanylacetonitrile (SALTDATA: FREE) is used as a building block in the production of pharmaceuticals for its ability to contribute to the development of new drugs and improve existing ones.

Upstream product

• 773837-37-9 sodium cyanide 
• 15833-63-3 (tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate 
• 124391-75-9 3-tetrahydrofuranmethanol 
• 184849-49-8 (tetrahydrofuran-3-yl)methyl methanesulfonate 
• 89181-22-6 3-(chloromethyl)tetrahydrofuran 
• 143-33-9 sodium cyanide 

Downstream Products

• 1072-94-2 2-(tetrahydrofuran-3-yl)acetaldehyde 

Relevant articles and documents

INDOLIZINE DERIVATIVES WHICH ARE APPLICABLE TO NEURODEGENERATIVE DISEASES

The present invention relates to indolizine compounds, and pharmaceutically acceptable compositions thereof, useful as antagonists of P2X7, and for the treatment of P2X7-related disorders.

Method for producing organic compounds by substituting halogen atoms

The invention pertains to a method in which a halogen atom of an organic compound is replaced with a group derived from a nucleophilic agent, at high yield and high efficiency, by the following method which includes a step of reacting the nucleophilic agent with an organic material having a halogen atom bonded to a carbon atom having four σ bonds, more specifically: a method for producing an organic compound having Q, the method including a step of reacting a compound represented by general formula (2) with an organic starting material having at least one halogen atom bonded to a carbon atom having four σ bonds so as to replace the halogen atom in the organic starting material with Q:MQa (wherein M represents an alkali metal atom, an alkali earth metal atom, or a rare earth metal atom; Q represents a moiety of an inorganic acid or an active hydrogen compound derived by eliminating a proton, wherein Q is a halogen atom different from the halogen atom in the organic starting material having the halogen atom bonded to the carbon atom having the four σ bonds; and a represents an integer of 1 to 3) in the presence of a compound represented by general formula (1) (wherein Z- represents an anion derived by eliminating a proton from an inorganic acid or an active hydrogen compound; R2 is the same or different; R2 each independently represent a C1-C10 hydrocarbon group or two R2 on the same nitrogen atom may be bonded with each other to form a ring with the nitrogen atom).