4765-46-2

Basic information

• Product Name: 1-Propanone, 1-(2-amino-4,5-dimethoxyphenyl)-
• CAS NO: 4765-46-2
• Molecular Formula: C11H15NO3
• Molecular Weight: 209.245
• Mol File: 4765-46-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1-Propanone, 1-(2-amino-4,5-dimethoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Propanone, 1-(2-amino-4,5-dimethoxyphenyl)-(4765-46-2)
• EPA Substance Registry System: 1-Propanone, 1-(2-amino-4,5-dimethoxyphenyl)-(4765-46-2)

Safety Data

• Hazardous Substances Data: 4765-46-2(Hazardous Substances Data)

Usage

Type of compound

aromatic ketone derivative

Functional groups

amino and methoxy

Common uses

synthesis of various pharmaceuticals and research chemicals

Potential applications

medicinal chemistry and organic synthesis

Value

unique structure and functional groups make it valuable for scientific research and drug development

Upstream product

• 6315-89-5 3,4-dimethoxyaniline 
• 26961-27-3 2-amino-4,5-dimethoxybenzonitrile 
• 925-90-6 ethylmagnesium bromide 
• 1835-04-7 ethyl 3,4-dimethoxyphenyl ketone 
• 91-16-7 1,2-dimethoxybenzene 
• 91134-62-2 1-(4,5-dimethoxy-2-nitrophenyl)-1-propanone 
• 107-12-0 propiononitrile 

Downstream Products

• 34314-99-3 N-(4,5-dimethoxy-2-propionylphenyl)formamide 
• 4015-32-1 quazodine 
• 1070245-88-3 1-(2-amino-4,5-dimethoxyphenyl)-1-phenyl-1-propanol 
• 924635-51-8 4-methyl-N-{4,5-dimethoxy-2-[1-(5-methylfuran-2-yl)propyl]phenyl}benzenesulfonamide 
• 871563-18-7 2-(1-hydroxypropyl)-4,5-dimethoxy-1-(4-methylphenylsulfonamido)benzene 
• 4765-85-9 4,5-dimethoxy-1-(4-methylphenylsulfonamido)-2-propionylbenzene 

Relevant articles and documents

IMINO SULFANONE INHIBITORS OF ENPP1

The present disclosure relates generally to inhibitors of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), compositions thereof, and methods of using said compounds and compositions thereof. More specifically, the present disclosure relates to sulfoximine- based inhibitors of ENPP1 of Formula (I) and methods of their use for treating disease mediated by ENPP1.

Simple route to 3-(2-indolyl)-1-propanones via a furan recyclization reaction

A simple route to 1-R-3-(2-indolyl)-1-propanones has been elaborated based on recyclization of 2-(2-aminobenzyl)furan derivatives. Being a modification of the Reissert indole synthesis, our approach employs the furan ring as a source of carbonyl function. This approach is general and allows varying of substituents in aromatic ring as well as in 3-position of indole nucleus.

Camptothecin derivatives

New campotothecin derivatives and a process for preparing same are disclosed, which are represented by the general formula: STR1 wherein R1 represents a lower alkyl group, R2 represents a hydrogen atom or an amino, hydroxyl, lower acylamino or lower alkoxy group, R3 represents a hydrogen or halogen atom or a lower alkyl, hydroxyl, lower alkoxy, nitro, amino, cyano or di(lower alkyl)amino group, R4 represents a hydrogen or halogen atom or a lower alkyl, hydroxyl, lower alkoxy, lower alkylthio, amino, cyano or di(lower alkyl)amino group, and R5 represents a hydrogen or halogen atom or a hydroxyl or lower alkoxy group, with the proviso that all of the R2, R3, R4 and R5 substituents should not be a hydrogen atom and also that if any one of the R2, R3, R4 and R5 is a hydroxyl or lower alkoxy group, all of the other three substituents should not be a hydrogen atom.