4765-59-7

Basic information

• Product Name: 4(1H)-Quinazolinone, 2-(4-nitrophenyl)-
• CAS NO: 4765-59-7
• Molecular Formula: C14H9N3O3
• Molecular Weight: 267.244
• Mol File: 4765-59-7.mol
• Article Data: 96

Chemical Properties

• CAS DataBase Reference: 4(1H)-Quinazolinone, 2-(4-nitrophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4(1H)-Quinazolinone, 2-(4-nitrophenyl)-(4765-59-7)
• EPA Substance Registry System: 4(1H)-Quinazolinone, 2-(4-nitrophenyl)-(4765-59-7)

Safety Data

• Hazardous Substances Data: 4765-59-7(Hazardous Substances Data)

Upstream product

• 26029-31-2 2-(4-nitro-phenyl)-2,3-dihydro-1H-quinazolin-4-one 
• 2735-14-0 1,2-bis(4-nitrophenyl)acetylene 
• 28144-70-9 anthranilic acid amide 
• 619-72-7 4-nitrobenzonitrile 
• 57699-45-3 p-tert-butoxybenzaldehyde 
• 40015-09-6 2-(4-nitrophenyl)-1H-indole 
• 100-13-0 4-nitrostyrene 
• 88-67-5 2-Iodobenzoic acid 
• 15723-90-7 4-nitrobenzamidine hydrochloride 
• 118-91-2 ortho-chlorobenzoic acid 
• 88-65-3 2-bromobenzoic-acid 
• 56222-10-7 N-(4-nitrobenzyl)acetamide 
• 838-57-3 ethyl 4-nitrobenzoylacetate 
• 99-99-0 1-methyl-4-nitrobenzene 

Downstream Products

• 83800-97-9 4-chloro-2-(4-nitrophenyl)quinazoline 
• 701290-17-7 N-(4-(4-oxo-3,4-dihydroquinazoline-2-yl)phenyl)acetamide 

Relevant articles and documents

Mn(OAc) 3Induced C-4 Arylations of Quinazoline 3-Oxides with Arylboronic Acids

The use of manganese triacetate as an oxidant component in the C-4 arylations of 2-aryl-quinazoline 3-oxides with arylboronic acids is reported. The new protocol was applied to prepare new 2,4-diarylated quinazoline 3-oxides in good to high yields. The me

A bagasse-supported magnetic manganese dioxide nanoparticle: applications in the selective aerobic oxidation of alcohols and one-pot tandem oxidative synthesis of quinazolinones

Magnetic manganese dioxide nanoparticles (MnO2-Fe3O4) were coated on sugarcane bagasse as a sugar industrial waste and bio-support (MnO2-Fe3O4@bagasse) via an in situ reduction strategy, in which potassium permanganate was used as the precursor of MnO2 and sugarcane bagasse as a bio-support and reducing agent of KMnO4. The synthesized bio-based catalyst was characterized by X-ray diffraction, thermogravimetric analysis, inductively coupled plasma optical emission spectroscopy, scanning electron microscopy, energy dispersive spectroscopy, Brunauer–Emmett–Teller surface area analysis, and vibrating sample magnetometer analysis. The catalyst was successfully utilized in the selective aerobic oxidation of primary and secondary benzylic alcohols to their corresponding carbonyl compounds and one-pot tandem oxidative synthesis of 2-(substituted)quinazoline-4(3H)-ones from the o-aminobenzamide and aromatic alcohols in the absence of oxidizing reagent or initiator. Graphical abstract: [Figure not available: see fulltext.]

Method for synthesizing 2 -phenylquinazolone compound by taking styrene compound as raw material

The invention discloses a method for synthesizing a 2-phenyl quinazolinone compound. The method comprises the steps of adopting a styrene compound and 2-aminobenzamide as reaction raw materials; underthe combined action of a palladium catalyst, a ligand and oxygen, reacting to obtain the 2-phenyl quinazolinone compound, wherein the reaction temperature is 80 DEG C to 110 DEG C, a reaction formulais as shown in the below figure, and R is hydrogen, fluorine, chlorine, bromine, methyl, trifluoromethyl, nitro or methoxyl. The method provided by the invention has the beneficial effects that the raw material styrene compound is cheap and easy to get, so that the method is more economical; a preparation method is simple and convenient to operate, and the obtained product is easy to post-process, so that the method is suitable for large-scale industrial production; no high temperature and high pressure is needed, and a reaction condition is mild; the method is short in reaction time, high efficient to react, high in yield, and higher in reaction efficiency after reaction amplification.