4770-36-9

Basic information

• Product Name: 1H-Indol-7-ol,1-acetyl-2,3-dihydro-(9CI)
• Synonyms: 1H-Indol-7-ol,1-acetyl-2,3-dihydro-(9CI);1-(7-hydroxyindolin-1-yl)ethanone;1-Acetyl-7-hydroxyindoline
• CAS NO: 4770-36-9
• Molecular Formula: C10H11NO2
• Molecular Weight: 177.2
• Product Categories: PYRROLE
• Mol File: 4770-36-9.mol
• Article Data: 3

Chemical Properties

• Melting Point: 114.5-115 °C
• Boiling Point: 411.9±45.0 °C(Predicted)
• Appearance: /
• Density: 1.272±0.06 g/cm3(Predicted)
• PKA: 8.66±0.20(Predicted)
• CAS DataBase Reference: 1H-Indol-7-ol,1-acetyl-2,3-dihydro-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indol-7-ol,1-acetyl-2,3-dihydro-(9CI)(4770-36-9)
• EPA Substance Registry System: 1H-Indol-7-ol,1-acetyl-2,3-dihydro-(9CI)(4770-36-9)

Safety Data

• Hazardous Substances Data: 4770-36-9(Hazardous Substances Data)

Usage

Derivative of indole

Heterocyclic aromatic organic compound

Dihydro derivative

Two hydrogen atoms added to the indole ring

Contains an acetyl group

Functional group derived from acetic acid

Potential applications

Pharmaceuticals and organic synthesis

Unique structure and properties

Important for researchers and chemists to understand its characteristics and behavior for potential uses in various fields.

Upstream product

• 105205-61-6 1-(2,3-Dihydro-1H-indol-7-yl)-ethanol 
• 16078-30-1 1-Acetyl-2,3-dihydro-1H-indole 
• 4770-38-1 7-hydroxy-indoline 
• 108-24-7 acetic anhydride 

Downstream Products

• 220657-62-5 2,3-dihydro-7-ethoxyindole 
• 220657-61-4 1-acetyl-7-ethoxy-2,3-dihydroindole 

Relevant articles and documents

FURTHER OBSERVATIONS ON THE LEWIS ACID-CATALYZED BENZYLIC HYDROPEROXIDE REARRANGEMENT: USE OF A BORON-TRIFLUORIDE/HYDROGEN PEROXIDE PREFORMED, AGED REAGENT

A preformed, aged reagent derived from boron trifluoride etherate and 90percent hydrogen peroxide (2:1-4:1 complex) has been found to be a useful reagent for promoting the benzylic hydroperoxide rearrangement of readily oxidizable substrates bearing a free, basic amine.The use of this procedure for introduction of the C-4 phenol of the C-4/C-5 selectively-protected o-catechol unit found in PDE-I and PDE-II, naturally-occuring phosphodiesterase inhibitors constituting the central and right-hand segments of the antitumor-antibiotic CC-1065, is detailed.

A SIMPLE SYNTHESIS OF 7-SUBSTITUTED 1-ACETYL-2,3-DIHYDROINDOLES

7-Cyano-, 7-hydroxy-, 7-methoxycarbonyl-, 7-methyl-, 7-nitro-, and 7-phenyl-1-acetyl-2,3-dihydroindoles are prepared in two steps (or one pot) from 1-acetyl-2,3-dihydroindole.