477254-69-6

Basic information

• Product Name: (S)-BoroLeu-(-)-Pinanediol-CF3COOH
• Synonyms: (S)-BoroLeu-(-)-Pinanediol-CF3COOH;4,6-Methano-1,3,2-benzodioxaborole-2-methanamine, hexahydro-3a,5,5-trimethyl-a-(2-methylpropyl)-, (aS,3aS,4S,6S,7aR)-, trifluoroacetate;4,6-Methano-1,3,2-benzodioxaborole-2-methanamine, hexahydro-3a,8,8-trimethyl-α-(2-methylpropyl)-, (αS,3aS,4S,6S,7aR)-, 2,2,2-trifluoroacetate (1:1);(1S)-(1S,2S,3R,5S)-pinanediol-1-ammoniumtrifluoroacetate-3-methylbutane-1-boronate
• CAS NO: 477254-69-6
• Molecular Formula: C₂HF₃O₂*C₁₅H₂₈BNO₂
• Molecular Weight: 379.2226696
• Mol File: 477254-69-6.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-BoroLeu-(-)-Pinanediol-CF3COOH(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-BoroLeu-(-)-Pinanediol-CF3COOH(477254-69-6)
• EPA Substance Registry System: (S)-BoroLeu-(-)-Pinanediol-CF3COOH(477254-69-6)

Safety Data

• Hazardous Substances Data: 477254-69-6(Hazardous Substances Data)

Usage

General Description

(S)-BoroLeu-(-)-Pinanediol-CF3COOH is a chemical compound consisting of three main components: BoroLeu, (-)-Pinanediol, and CF3COOH. BoroLeu is a boron-containing leucine derivative, while (-)-Pinanediol is a chiral auxiliary commonly used in organic synthesis for stereocontrol. CF3COOH is a trifluoroacetic acid, which is a strong acid commonly used in organic chemistry for various reactions and as a solvent. The combination of these components in (S)-BoroLeu-(-)-Pinanediol-CF3COOH likely serves as a reagent or chiral catalyst in organic synthesis reactions, enabling controlled and selective formation of chiral compounds. This chemical compound is likely to be of interest in the development of new pharmaceuticals and other chiral materials.

Upstream product

• 1135491-84-7 (1S)-(S)-pinanediol 1-bis(trimethylsilyl)amino-3-methylbutane-1-boronate 
• 76-05-1 trifluoroacetic acid 
• 514820-48-5 1,1,1-trimethyl-N-{(1R)-3-methyl-1-[(3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methano-1,3,2-benzodioxaborol-2-yl]butyl}-N-(trimethylsilyl)silanamine 

Downstream Products

• 1187479-72-6 (1S,2S,3R,5S)-pinanediol N-BOC-L-phenylalanine-L-leucine boronate 

Relevant articles and documents

SYNTHESIS OF BORONIC ESTER AND ACID COMPOUNDS

The invention relates to the synthesis of boronic ester and acid compounds. More particularly, the invention provides improved synthetic processes for the large-scale production of boronic ester and acid compounds, including the peptide boronic acid proteasome inhibitor bortezomib.