477727-56-3

Basic information

• Product Name: 2-Pyrimidinamine, 4-(5-bromo-2-methoxyphenyl)-6-chloro-
• CAS NO: 477727-56-3
• Molecular Formula: C11H9BrClN3O
• Molecular Weight: 314.569
• Mol File: 477727-56-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Pyrimidinamine, 4-(5-bromo-2-methoxyphenyl)-6-chloro-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pyrimidinamine, 4-(5-bromo-2-methoxyphenyl)-6-chloro-(477727-56-3)
• EPA Substance Registry System: 2-Pyrimidinamine, 4-(5-bromo-2-methoxyphenyl)-6-chloro-(477727-56-3)

Safety Data

• Hazardous Substances Data: 477727-56-3(Hazardous Substances Data)

Upstream product

• 477727-55-2 2-Amino-6-(5-bromo-2-methoxy-phenyl)-3H-pyrimidin-4-one 
• 56-05-3 2-Amino-4,6-dichloropyrimidine 
• 89694-45-1 5-bromo-2-methoxyphenylboronic acid 

Downstream Products

• 1035226-79-9 5-bromo-4-(5-bromo-2-methoxyphenyl)-6-chloropyrimidin-2-amine 
• 774608-07-0 4-(5-Bromo-2-hydroxy-phenyl)-6-chloro-pyrimidin-2-ylamine 

Relevant articles and documents

NOVEL TRICYCLIC AND HETEROTRICYCLIC DERIVATIVES, PROCESSES FOR PREPARING THEM, PHARMACEUTICAL COMPOSITIONS THEREOF

The present invention concerns novel tricyclic and heterotricyclic derivatives, processes for preparing them, pharmaceutical compositions containing them and their use as pharmaceuticals.

Synthesis, SAR, and antitumor properties of diamino-C,N-diarylpyrimidine positional isomers: Inhibitors of lysophosphatidic acid acyltransferase-β

2,4-Diamino-N4,6-diarylpyrimidines were identified as potent, isoform specific inhibitors of lysophosphatidic acid acyltransferase-β (LPAAT-β). Active inhibitors also blocked proliferation of tumor cell lines in vitro. The effect of 2j in an in