477935-11-8

Basic information

• Product Name: (4-hydroxy-phenylimino)-(1H-indol-3-yl)-acetonitrile
• Synonyms: (4-hydroxy-phenylimino)-(1H-indol-3-yl)-acetonitrile
• CAS NO: 477935-11-8
• Molecular Weight: 261.283
• Mol File: 477935-11-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-hydroxy-phenylimino)-(1H-indol-3-yl)-acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (4-hydroxy-phenylimino)-(1H-indol-3-yl)-acetonitrile(477935-11-8)
• EPA Substance Registry System: (4-hydroxy-phenylimino)-(1H-indol-3-yl)-acetonitrile(477935-11-8)

Safety Data

• Hazardous Substances Data: 477935-11-8(Hazardous Substances Data)

Upstream product

• 123-30-8 4-amino-phenol 
• 487-89-8 Indole-3-carboxaldehyde 
• 143-33-9 sodium cyanide 
• 118380-30-6 ?(E)-4-((1H-indol-3-yl)methyleneamino)phenol 

Downstream Products

• 1477-49-2 3-indolylglyoxylic acid 

Relevant articles and documents

A new facile method for preparation of heterocyclic α-iminonitriles and α-oxoacetic acid from heterocyclic aldehydes, p-aminophenol, and sodium cyanide

Very efficient, simple, and high yield procedures for the transformation of heterocyclic aldehydes into heterocyclic methylidene-p-hydroxyanilines, heterocyclic α-iminonitriles, and finally into heterocyclic α-oxoacetic acids were described. Considering that many of these compounds have biological activity, the synthetic methodology was optimized using readily available, inexpensive starting materials, and the purification of the product involved only simple crystallization.