478131-76-9

Basic information

• Product Name: (3S,4R)-3-(dimesitylsilyl)-4,5-O-(3-pentilidene)-4,5-dihydroxypentanoate
• Synonyms: (3S,4R)-3-(dimesitylsilyl)-4,5-O-(3-pentilidene)-4,5-dihydroxypentanoate
• CAS NO: 478131-76-9
• Molecular Weight: 496.762
• Mol File: 478131-76-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3S,4R)-3-(dimesitylsilyl)-4,5-O-(3-pentilidene)-4,5-dihydroxypentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4R)-3-(dimesitylsilyl)-4,5-O-(3-pentilidene)-4,5-dihydroxypentanoate(478131-76-9)
• EPA Substance Registry System: (3S,4R)-3-(dimesitylsilyl)-4,5-O-(3-pentilidene)-4,5-dihydroxypentanoate(478131-76-9)

Safety Data

• Hazardous Substances Data: 478131-76-9(Hazardous Substances Data)

Upstream product

• 643-01-6 L-mannitol 

Relevant articles and documents

Utilization of 1-Oxa-2,2-(dimesityl)silacyclopentane acetals in the stereoselective synthesis of polyols

We have developed a route for the stereoselective synthesis of 1-oxa-2,2-(dimesityl)silacyclopentane acetals, intermediates in the synthesis of highly functionalized 1,3-diols. This route involves a diastereoselective conjugate addition reaction of a hydrosilyl anion, a subsequent diastereoselective enolate alkylation, and a fluoride-catalyzed intramolecular hydrosilylation reaction to afford the oxasilacyclopentane acetal. A highly selective nucleophilic substitution reaction, followed by oxidation of the C-Si bond, leads to the desired polyol. Copyright