4783-77-1Relevant articles and documents
Identification of an Oxalamide Ligand for Copper-Catalyzed C?O Couplings from a Pharmaceutical Compound Library
Chan, Vincent S.,Krabbe, Scott W.,Li, Changfeng,Sun, Lijie,Liu, Yue,Nett, Alex J.
, (2019/04/30)
A typical pharmaceutical compound library is stocked with molecular diversity and could provide a platform for the discovery of new ligand structures. Herein, we describe the use of this approach in combination with high throughput screening to identify N,N’-bis(thiophene-2-ylmethyl)oxalamide as a ligand that is generally effective for copper-catalyzed C?O cross-couplings to prepare both biarylethers as well as phenols under mild conditions.
Method for synthesizing o-alkenyl phenol derivate
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Paragraph 0166-0169, (2017/08/29)
The invention discloses a method for synthesizing o-alkenyl phenol derivate. The synthesizing method is characterized in that Uhlmann C-O coupling reaction, olefin reaction and pyridine group removing reaction are carried out to prepare the o-alkenyl phen
C-H functionalization of phenols using combined ruthenium and photoredox catalysis: In situ generation of the oxidant
Fabry, David C.,Ronge, Meria A.,Zoller, Jochen,Rueping, Magnus
supporting information, p. 2801 - 2805 (2015/03/04)
A combination of ruthenium and photoredox catalysis allowed the ortho olefination of phenols. Using visible light, the direct C-H functionalization of o-(2-pyridyl) phenols occurred, and diverse phenol ethers were obtained in good yields. The regeneration of the ruthenium catalyst was accomplished by a photoredox-catalyzed oxidative process.