478868-76-7

Basic information

• Product Name: 4-(4-Chloro-2-methyl-phenyl)-3-[(Z)-hydroxyimino]-2,4-dioxo-butyric acid ethyl ester
• CAS NO: 478868-76-7
• Molecular Weight: 297.695
• Mol File: 478868-76-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(4-Chloro-2-methyl-phenyl)-3-[(Z)-hydroxyimino]-2,4-dioxo-butyric acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-Chloro-2-methyl-phenyl)-3-[(Z)-hydroxyimino]-2,4-dioxo-butyric acid ethyl ester(478868-76-7)
• EPA Substance Registry System: 4-(4-Chloro-2-methyl-phenyl)-3-[(Z)-hydroxyimino]-2,4-dioxo-butyric acid ethyl ester(478868-76-7)

Safety Data

• Hazardous Substances Data: 478868-76-7(Hazardous Substances Data)

Upstream product

• 37074-38-7 o-(Methyl)-p-chloroacetophenone 
• 478868-69-8 4-(4-chloro-2-methyl-phenyl)-2,4-dioxo-butyric acid ethyl ester 

Downstream Products

• 478869-16-8 3-(4-chloro-2-methyl-phenyl)-2,5-dimethyl-2,6-dihydro-pyrazolo[4,3-d]pyrimidin-7-one 
• 478869-00-0 4-amino-5-(4-chloro-2-methyl-phenyl)-1-methyl-1H-pyrazole-3-carboxylic acid ethyl ester 
• 478869-24-8 7-chloro-3-(4-chloro-2-methyl-phenyl)-2,5-dimethyl-2H-pyrazolo[4,3-d]pyrimidine 
• 478868-84-7 5-(4-chloro-2-methyl-phenyl)-1-methyl-4-nitroso-1H-pyrazole-3-carboxylic acid ethyl ester 

Relevant articles and documents

3-Aryl pyrazolo[4,3-d]pyrimidine derivatives: Nonpeptide CRF-1 antagonists.

The synthesis of a series of 3-aryl pyrazolo[4,3-d]pyrimidines as potential corticotropin-releasing factor (CRF-1) antagonists is described. The effects of substitution on the aromatic ring, the amino group and the pyrazolo ring on CRF-1 receptor binding