4789-76-8

Basic information

• Product Name: 4-methyl-2-phenyl-quinoline
• Synonyms: 4-methyl-2-phenyl-quinoline;2-Phenyl-4-methylquinoline;2-Phenyllepidine
• CAS NO: 4789-76-8
• Molecular Formula: C₁₆H₁₃N
• Molecular Weight: 219.28
• Mol File: 4789-76-8.mol
• Article Data: 109

Chemical Properties

• Boiling Point: 370.8°Cat760mmHg
• Flash Point: 161.4°C
• Appearance: /
• Density: 1.105g/cm³
• Vapor Pressure: 2.3E-05mmHg at 25°C
• Refractive Index: 1.641
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-methyl-2-phenyl-quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-2-phenyl-quinoline(4789-76-8)
• EPA Substance Registry System: 4-methyl-2-phenyl-quinoline(4789-76-8)

Safety Data

• Hazardous Substances Data: 4789-76-8(Hazardous Substances Data)

Usage

Description

4-methyl-2-phenyl-quinoline is a quinoline derivative with the molecular formula C17H13N. It is a yellow, crystalline solid that is insoluble in water but soluble in organic solvents. This chemical compound is commonly used in organic synthesis and as a precursor in the production of pharmaceuticals and dyes. It has also been studied for its potential biological properties, including its use as a fluorescent probe and its potential as an anti-cancer agent. Furthermore, 4-methyl-2-phenyl-quinoline has been utilized as a building block in the synthesis of various heterocyclic compounds with potential applications in medicine and materials science.

Uses

Used in Organic Synthesis:
4-methyl-2-phenyl-quinoline is used as a chemical intermediate for the synthesis of various organic compounds. Its unique structure allows it to be a versatile building block in the creation of new molecules with potential applications in various industries.
Used in Pharmaceutical Production:
As a precursor, 4-methyl-2-phenyl-quinoline is used in the production of pharmaceuticals. Its presence in the synthesis process contributes to the development of new drugs with potential therapeutic benefits.
Used in Dye Manufacturing:
This quinoline derivative is also used in the manufacturing of dyes, where its yellow color and chemical properties are harnessed to create a range of colorants for various applications.
Used in Fluorescent Probe Development:
4-methyl-2-phenyl-quinoline is utilized as a fluorescent probe in biological and chemical research. Its fluorescent properties allow it to be used in imaging and detection techniques, providing valuable insights into various scientific studies.
Used in Anti-Cancer Research:
4-methyl-2-phenyl-quinoline has been studied for its potential as an anti-cancer agent. Its biological properties are being investigated for their ability to target and treat cancer cells, offering a promising avenue for the development of new cancer therapies.
Used in Heterocyclic Compound Synthesis:
4-methyl-2-phenyl-quinoline serves as a building block in the synthesis of heterocyclic compounds, which have potential applications in medicine and materials science. Its role in creating these complex molecules contributes to the advancement of various fields, including drug discovery and material development.

InChI:InChI=1/C16H13N/c1-12-11-16(13-7-3-2-4-8-13)17-15-10-6-5-9-14(12)15/h2-11H,1H3

Upstream product

• 491-35-0 C₆H₄NCH₂CHCCH₂ 
• 60-29-7 diethyl ether 
• 591-51-5 phenyllithium 
• 551-93-9 2-aminoacetophenone 
• 98-86-2 acetophenone 
• 94-36-0 dibenzoyl peroxide 
• 634-47-9 2-chloro-4-methylquinoline 
• 98-80-6 phenylboronic acid 
• 143-66-8 sodium tetraphenyl borate 
• 116-11-0 2-Methoxypropene 
• 1750-36-3 (E)-N-benzylidenebenzenamine 
• 14365-89-0 4-(4-methyl-quinolin-2-yl)-phenol 
• 172041-18-8 4-methyl-2-phenyl-1,2,3,4-tetrahydroquinoline 
• 98-85-1 1-Phenylethanol 

Downstream Products

• 78450-59-6 1,1,1-trichloro-3-(2-phenyl-[4]quinolyl)-propan-2-ol 
• 117839-38-0 2-phenyl-4-quinolinecarboxaldehyde 
• 3475-16-9 4-methyl-2-phenylquinoline 1-oxide 
• 332124-42-2 3-(2-phenyl-4-quinolinyl)benzoic acid ethyl ester 
• 14365-89-0 4-(4-methyl-quinolin-2-yl)-phenol 
• 580-38-1 4-(4-methyl-[2]quinolyl)-aniline 
• 47492-97-7 N,N-diethyl-N'-(2-phenyl-[4]quinolylmethyl)-propanediyldiamine 
• 14365-92-5 4-methyl-2-(4-nitrophenyl)quinoline 

Relevant articles and documents

Tautomerism in ketomethyl quinolines. Part 3. 4-ketomethylquinolines

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Phenanthrenequinone-Sensitized Photocatalytic Synthesis of Polysubstituted Quinolines from 2-Vinylarylimines

Visible-light-excited 9,10-phenanthrenequinone (PQ*) was used as a photocatalyst for the synthesis of polysubstituted quinolines via the electrocyclization of 2-vinylarylimines. Up to quantitative yields of 2,4-disubstituted quinolines were received after 1 h of excitation with blue LEDs at room temperature when MgCO3 was used as an additive in DCM. On the basis of experimental and DFT studies, we propose that PQ? induces one-electron oxidation of the imine substrate that triggers the electrocyclization mechanism.

Novel anti-solvent quenching near-infrared two-zone dye and preparation method thereof Preparation method and application thereof

The invention provides a novel anti-solvent quenching near-infrared two-zone dye and a preparation method and application thereof, and relates to a novel anti-solvent quenching NIR-II dye containing a nitrogen heterocyclic ring. Experiments show that the

Magnetite (Fe3O4) nanoparticles-supported dodecylbenzenesulfonic acid as a highly efficient and green heterogeneous catalyst for the synthesis of substituted quinolines and 1-amidoalkyl-2-naphthol derivatives

Abstract: Magnetically retrievable, magnetite (Fe3O4) nanoparticles-supported dodecylbenzenesulfonic acid (DDBSA@MNP) was synthesized and characterized through different analytical techniques such as TEM, XRD, FTIR, TGA, SEM, EDX and