479630-66-5

Basic information

• Product Name: Benzenepropanoic acid, a-[[(trifluoromethyl)sulfonyl]oxy]-, methyl ester
• CAS NO: 479630-66-5
• Molecular Formula: C11H11F3O5S
• Molecular Weight: 312.267
• Mol File: 479630-66-5.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, a-[[(trifluoromethyl)sulfonyl]oxy]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, a-[[(trifluoromethyl)sulfonyl]oxy]-, methyl ester(479630-66-5)
• EPA Substance Registry System: Benzenepropanoic acid, a-[[(trifluoromethyl)sulfonyl]oxy]-, methyl ester(479630-66-5)

Safety Data

• Hazardous Substances Data: 479630-66-5(Hazardous Substances Data)

Upstream product

• 13674-16-3 methyl 2-hydroxy-3-phenylpropanoate 
• 407-25-0 trifluoroacetic anhydride 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 828-01-3 phenyllactic acid 

Downstream Products

• 877379-64-1 methyl 3-phenyl-2-{[6-(5-phenyl-1H-pyrrol-2-yl)-2-naphthyl]oxy}propanoate 
• 1445961-68-1 2-{4-[5-chloro-2-(1H-1,2,3,4-tetrazol-1-yl)phenyl]-2-oxo-1,2-dihydropyridin-1-yl}-3-phenylpropanoic acid 
• 926025-06-1 2-(5-nitro-indol-1-yl)-3-phenyl-propionic acid methyl ester 
• 877379-02-7 methyl 2-({6-[2-(1-methyl-1H-indol-3-yl)-1,3-oxazol-5-yl]-2-naphthyl}oxy)-3-phenylpropanoate 
• 877378-93-3 methyl 2-({6-[2-(1-benzyl-1H-indol-3-yl)-1,3-oxazoI-5-yl]-2-naphthyl}oxy)-3-phenylpropanoate 
• 848853-47-4 methyl 2-[(3-bromo-4'-{[[(2-butyl-1-benzofuran-3-yl)carbonyl](methyl)-amino]methyl}-1,1'-biphenyl-4-yl)oxy]-3-phenylpropanoate 
• 221525-83-3 (S)-6-Benzyloxycarbonylamino-2-[((2S,3S)-1-{(S)-2-[3-(tert-butoxycarbonylamino-methyl)-phenylamino]-3-phenyl-propionyl}-3-phenyl-pyrrolidine-2-carbonyl)-amino]-hexanoic acid methyl ester 
• 221525-91-3 (S)-6-Benzyloxycarbonylamino-2-[((2S,3S)-1-{(S)-2-[3-(tert-butoxycarbonylamino-methyl)-phenylamino]-3-phenyl-propionyl}-3-phenyl-pyrrolidine-2-carbonyl)-amino]-hexanoic acid 
• 221526-03-0 [4-((3S,8S,9S,12S)-3-Benzyl-4,10,13-trioxo-8-phenyl-2,5,11,14-tetraaza-tricyclo[14.3.1.0^5,9]icosa-1⁽²⁰⁾,16,18-trien-12-yl)-butyl]-carbamic acid benzyl ester 
• 221525-75-3 (S)-2-[3-(tert-Butoxycarbonylamino-methyl)-phenylamino]-3-phenyl-propionic acid 

Relevant articles and documents

PYRIDONE OR PYRIMIDONE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

Provided is a pyridone or pyrimidone derivative(s) represented by general formula (I) and its preparation method and use. Substituents of the compound of general formula (I) are defined the same as in the specification.

Thiazolo-naphthyl acids

The present invention relates to thiazolo-naphthyl acids of the formula and methods of using them to modulate PAI-1 expression and to treat PAI-1 related disorders.

6-(Aryl-amido or aryl-amidomethyl)-naphthalen-2-yloxy-acidic derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1)

This invention provides novel compounds, pharmaceutical compositions and methods of treating thrombotic disorders in mammals, the compounds having the formula: Wherein: Ar is phenyl, naphthyl, furanyl, benzofuranyl, indolyl, pyrazolyl, oxazolyl, fluorenyl, phenylcycloalkane where the cycloalkane can be cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl and Ar can be optionally substituted by 1 to 3 groups selected from C1-C6 alkyl, C1-C6 alkoxy, hydroxy, phenyl-(CH2)0-6—, phenyl-(CH2)0-6O—, C3-C6 cycloalkyl, —(CH2)—C3-C6 cycloalkyl, halogen, C1-C3 perflouroalkyl and C1-C3 perfluoroalkoxy where phenyl can be substituted with from 1 to 3 groups selected from C1-C6 alkyl, C1-C6 alkoxy, phenyl, halogen, trifluoromethyl or trifluoromethoxy; R1 is hydrogen, C1-C6 alkyl or phenyl-(CH2)1-6— where phenyl can be substituted with C1-C6 alkyl, C1-C6 alkoxy, halo, trifluoromethyl or trifluoromethoxy; R2 and R3 are H, C1-C6 alkyl, phenyl-(CH2)0-3—, halo and C1-C3 perfluoroalkyl where phenyl can be substituted with C1-C6 alkyl, C1-C6 alkoxy, halo, trifluoromethyl or trifluoromethoxy; R4 is —CHR5CO2H or —CH2-tetrazole where R5 is H or benzyl; and n=0 or 1; or a pharmaceutically acceptable salt or ester form thereof.