479673-26-2

Basic information

• Product Name: (12S, [13S,] [14S,] [19R,] [20R,] [21R,] 22S)-21-(TERT-BUTYLDIMETHYLSILANYLOXY)-13,19-[BIS-(4-METHOXYBENZYLOXY)-12,] 14,20, 22-tetramethylhexacosa-10,15, 23, 25-TETRAEN-1-(TERT-Butyldimethylsilanyl)-ol
• Synonyms: (12S, [13S,] [14S,] [19R,] [20R,] [21R,] 22S)-21-(TERT-BUTYLDIMETHYLSILANYLOXY)-13,19-[BIS-(4-METHOXYBENZYLOXY)-12,] 14,20, 22-tetramethylhexacosa-10,15, 23, 25-TETRAEN-1-(TERT-Butyldimethylsilanyl)-ol
• CAS NO: 479673-26-2
• Molecular Weight: 947.584
• Mol File: 479673-26-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (12S, [13S,] [14S,] [19R,] [20R,] [21R,] 22S)-21-(TERT-BUTYLDIMETHYLSILANYLOXY)-13,19-[BIS-(4-METHOXYBENZYLOXY)-12,] 14,20, 22-tetramethylhexacosa-10,15, 23, 25-TETRAEN-1-(TERT-Butyldimethylsilanyl)-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (12S, [13S,] [14S,] [19R,] [20R,] [21R,] 22S)-21-(TERT-BUTYLDIMETHYLSILANYLOXY)-13,19-[BIS-(4-METHOXYBENZYLOXY)-12,] 14,20, 22-tetramethylhexacosa-10,15, 23, 25-TETRAEN-1-(TERT-Butyldimethylsilanyl)-ol(479673-26-2)
• EPA Substance Registry System: (12S, [13S,] [14S,] [19R,] [20R,] [21R,] 22S)-21-(TERT-BUTYLDIMETHYLSILANYLOXY)-13,19-[BIS-(4-METHOXYBENZYLOXY)-12,] 14,20, 22-tetramethylhexacosa-10,15, 23, 25-TETRAEN-1-(TERT-Butyldimethylsilanyl)-ol(479673-26-2)

Safety Data

• Hazardous Substances Data: 479673-26-2(Hazardous Substances Data)

Upstream product

• 672296-75-2 (Z)-(2R,3S,4S)-15-(tert-Butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-2,4-dimethyl-pentadec-5-enal 
• 479673-41-1 (2R,3R,4S,5R)-3,8-Bis-(tert-butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxy)-2,4-dimethyl-octanoic acid 2,6-dimethyl-phenyl ester 
• 479673-24-0 (2R,3R,4R,5R)-8-(tert-butyldimethylsilanyloxy)-3-hydroxy-5-(4-methoxybenzyloxy)-2,4-dimethyloctanoic acid, 2,6-dimethylphenyl ester 
• 479673-25-1 (1R,2R,3S,4S,5Z)-1-{3-(tert-butyldimethylsilanyloxy)-1-[3-(tert-butyldimethylsilanyloxy)propyl]-2,4-dimethylocta-5,7-dienyloxymethyl}-4-methoxybenzene 
• 479673-58-0 (Z)-(2S,3S,4S)-15-(tert-Butyl-dimethyl-silanyloxy)-3-(4-methoxy-benzyloxy)-2,4-dimethyl-pentadec-5-en-1-ol 
• 479673-44-4 tert-Butyl-{(Z)-(S)-12-[(4S,5S)-2-(4-methoxy-phenyl)-5-methyl-[1,3]dioxan-4-yl]-tridec-10-enyloxy}-dimethyl-silane 
• 479673-42-2 (2S,3S,4R,5R)-3,8-bis(tert-butyldimethylsilanyloxy)-5-(4-methoxybenzyloxy)-2,4-dimethyloctan-1-ol 
• 623926-35-2 (Z)-(5S,6S,7S,8R)-11-iodo-8-(4-methoxybenzyloxy)-5,7-dimethylundeca-1,3-dien-6-yl tert-butyldimethylsilyl ether 
• 479673-43-3 (Z)-(4R,5S,6S,7S)-6-(tert-butyldimethylsilanyloxy)-4-(4-methoxybenzyloxy)-5,7-dimethylundeca-8,10-dien-1-ol 
• 479673-36-4 (2S)-tert-butyl-{(4R,5S)-2-[2-(4-methoxyphenyl)-5-methyl[1,3]dioxan-4-yl]propoxy}dimethylsilane 
• 183565-25-5 (R)-4-Benzyl-3-[(2R,3S,4S)-5-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-2,4-dimethyl-pentanoyl]-oxazolidin-2-one 
• 479673-37-5 (2S)-2-[(4R,5S)-2-(4-methoxyphenyl)-5-methyl[1,3]dioxan-4-yl]propan-1-ol 
• 154919-93-4 (S)-4-Benzyl-3-[(2S,3R)-6-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-2-methyl-hexanoyl]-oxazolidin-2-one 
• 139670-36-3 10-(tert-butyldimethylsilanyloxy)decanal 

Downstream Products

• 479673-45-5 (10Z,15Z,23Z)-(12S,13S,14S,19R,20S,21S,22S)-21-(tert-Butyl-dimethyl-silanyloxy)-13,19-bis-(4-methoxy-benzyloxy)-12,14,20,22-tetramethyl-hexacosa-10,15,23,25-tetraen-1-ol 
• 479673-27-3 (10Z,15Z,23Z)-(12S,13S,14S,19R,20S,21S,22S)-21-(tert-Butyl-dimethyl-silanyloxy)-13,19-bis-(4-methoxy-benzyloxy)-12,14,20,22-tetramethyl-hexacosa-10,15,23,25-tetraenoic acid 
• 479673-46-6 (10Z,15Z,23Z)-(12S,13S,14S,19R,20R,21S,22S)-21-Hydroxy-13,19-bis-(4-methoxy-benzyloxy)-12,14,20,22-tetramethyl-hexacosa-10,15,23,25-tetraenoic acid 
• 479673-47-7 (11Z,16Z)-(13S,14S,15S,20R,21S,22S)-14,20-Bis-(4-methoxy-benzyloxy)-13,15,21-trimethyl-22-((Z)-(S)-1-methyl-penta-2,4-dienyl)-oxacyclodocosa-11,16-dien-2-one 

Relevant articles and documents

ANALOGS OF DISCODERMOLIDE AND DICTYOSTATIN-1, INTERMEDIATES THEREFOR AND METHODS OF SYNTHESIS THEREOF

A compound of the following structure: wherein R1 is H, an alkyl group, an aryl group, an alkenyl group, an alkynyl group, or a halogen atom; R2 is H, an alkyl group, an aryl group, a benzyl group, a trityl group, -SiRaRbRc, CH2ORd, or CORe; Ra, Rb and Rc are independently an alkyl group or an aryl group; Rd is an alkyl group, an aryl group, an alkoxylalkyl group, -RiSiRaRbRc or a benzyl group, wherein Ri is an alkylene group; Re is an alkyl group, an allyl group, a benzyl group, an aryl group, an alkoxy group, or -NRgRh, wherein Rg and Rh are independently H, an alkyl group or an aryl group; R3 is (CH2)n where n is and integer in the range of 0 to 5, -CH2CH(CH3)-, -CH=CH-, -CH=C(CH3)-, or -C=-C-; R4 is (CH2)p where p is an integer in the range of 4 to 12, -(CHRkl)yl (CHRk2)y2(CHRk3)y3(CHRk4)y4(CHRk5)y5C(Rsl )=C(Rs2)C(Rs3)=C(Rs4)-, -(CHRk1 )yl (CHRk2)y2(CHRk3)y3(CHRk4)y4(CHRk5)y5CH(RsI)CH(Rs2)C(Rs3)=C(Rs4)-, -(CHRk1)yl (CHRk2)y2(CHRk3)y3(CHRk4)y4(CHRks)y5C(Rsl)=C(Rs2)CH(Rs3)CH(Rs4)-, -(CHRkI )yl (CHRk2)y2(CHRk3)y3(CHRk4)y4(CHRk5)y5CH(Rsl)CH(Rs2)CH(Rs3)CH(R s4)-,wherein y1 and y2 are 1 and y3, y4 and y5 are independently 0 or 1, Rk1, Rk2, Rk3, Rk4 and Rk5 are independently H, CH3, or OR2a, and Rs1,Rs2, Rs3, and Rs4 are independently H or CH3, wherein R2a is H, an alkyl group, an aryl group, a benzyl group, a trityl group, -SiRaRbRc, CH2ORd, or CORe; and R5 is H or OR2b, wherein R2b is H, an alkyl group, an aryl group, an aryl group, a benzyl group, a trityl group, -SiRaRbRc, CH2ORd, or CORe; provided that the compound is not dictyostatin 1.