480438-50-4

Basic information

• Product Name: 3-CHLORO-5-FLUOROPHENYLMAGNESIUM BROMIDE
• Synonyms: 3-CHLORO-5-FLUOROPHENYLMAGNESIUM BROMIDE;3-CHLORO-5-FLUOROPHENYLMAGNESIUM BROMID&;3-chloro-5-fluorophenylmagnesium bromide solution;3-Chloro-5-fluorophenylmagnesium bromide 0.5M in THF;3-Chloro-5-fluorophenylmagnesium bromide solution 0.5 in THF;3-Chloro-5-fluorophenylmagnesium bromide, 0.5M solution in THF, AcroSeal;3-Chloro-5-fluorophenylMagnesiuM broMide, 0.50 M in 2-MeTHF;broMo-(3-chloro-5-fluoro-phenyl)MagnesiuM
• CAS NO: 480438-50-4
• Molecular Formula: C₆H₃BrClFMg
• Molecular Weight: 233.75
• Product Categories: Aryl;Grignard Reagents;Organometallic Reagents
• Mol File: 480438-50-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 65 °C
• Flash Point: 1 °F
• Appearance: Yellow to brown/Liquid
• Density: 0.968 g/mL at 25 °C
• Storage Temp.: 2-8°C
• Water Solubility: Reacts with water.
• Sensitive: Air & Moisture Sensitive
• CAS DataBase Reference: 3-CHLORO-5-FLUOROPHENYLMAGNESIUM BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-CHLORO-5-FLUOROPHENYLMAGNESIUM BROMIDE(480438-50-4)
• EPA Substance Registry System: 3-CHLORO-5-FLUOROPHENYLMAGNESIUM BROMIDE(480438-50-4)

Safety Data

• Hazard Codes: F,C,Xn
• Statements: 11-14-19-22-34-40-36/37
• Safety Statements: 16-26-33-36/37/39-45-36/37
• RIDADR: UN 2924 3/PG 2
• WGK Germany: 1
• HazardClass: 3
• Hazardous Substances Data: 480438-50-4(Hazardous Substances Data)

Usage

Description

3-CHLORO-5-FLUOROPHENYLMAGNESIUM BROMIDE is an organometallic compound that serves as a key intermediate in various chemical reactions. It is characterized by its reactivity and ability to form a wide range of organic compounds, making it a valuable asset in the field of organic synthesis.

Uses

Used in Organic Synthesis:
3-CHLORO-5-FLUOROPHENYLMAGNESIUM BROMIDE is used as a reagent for the formation of various organic compounds. Its unique properties allow it to participate in a range of reactions, including cross-coupling and addition reactions, leading to the synthesis of complex molecules.
Used in Pharmaceutical Industry:
3-CHLORO-5-FLUOROPHENYLMAGNESIUM BROMIDE is used as an intermediate for the synthesis of pharmaceutical compounds. Its versatility in forming different organic molecules makes it a valuable tool in the development of new drugs and therapeutic agents.
Used in Agrochemicals:
3-CHLORO-5-FLUOROPHENYLMAGNESIUM BROMIDE is used as a building block for the development of agrochemicals, such as pesticides and herbicides. Its ability to form a variety of organic compounds contributes to the creation of effective and targeted agrochemical products.
Used in Dye Industry:
3-CHLORO-5-FLUOROPHENYLMAGNESIUM BROMIDE is used as a precursor in the synthesis of dyes and pigments. Its reactivity and ability to form diverse organic molecules make it a valuable component in the production of a wide range of dyes with different properties and applications.

InChI:InChI=1/C6H3ClF.BrH.Mg/c7-5-2-1-3-6(8)4-5;;/h2-4H;1H;/q;;+1/p-1/rC6H3BrClFMg/c7-10-6-2-4(8)1-5(9)3-6/h1-3H

Upstream product

• 33863-76-2 1-bromo-3-chloro-5-fluorobenzene 
• 7439-95-4 magnesium 

Downstream Products

• 1146191-45-8 C₁₉H₂₃ClFNO 
• 1422424-57-4 C₁₂H₁₃ClFN 
• 1422424-58-5 C₁₂H₁₃ClFN 
• 1422424-56-3 C₁₇H₂₃ClFNO₃ 
• 929565-56-0 3-chloro-1-(3-chloro-5-fluorophenyl)propan-1-one 
• 1227472-52-7 tert-butyl (3RS)-3-(3-chloro-5-fluorophenyl)-3-hydroxy-1-oxa-8-azaspiro[4.5]decane-8-carboxylate 
• 1453849-12-1 1-(1-(3-chloro-5-fluorophenyl)-2-hydroxyethyl)-4-(2-((tetrahydro-2H-pyran-4-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one 

Relevant articles and documents

RENIN INHIBITORS

Described are compounds that bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with aspartic protease activity. Also described are methods of use of the compounds described herein in ameliorating or treating aspartic protease related disorders in a subject in need thereof.