4810-79-1

Basic information

• Product Name: 4-ISOBUTYL-PYRIDINE
• Synonyms: 4-ISOBUTYL-PYRIDINE;4-(2-Methylpropyl)pyridine;1-Isobutyl-1H-pyrazole-4-carboxylicacid
• CAS NO: 4810-79-1
• Molecular Formula: C₉H₁₃N
• Molecular Weight: 135.21
• EINECS: 225-376-5
• Mol File: 4810-79-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 197-199°C
• Flash Point: 69.2°C
• Appearance: /
• Density: 0.908g/cm³
• Vapor Pressure: 0.468mmHg at 25°C
• Refractive Index: 1.491
• CAS DataBase Reference: 4-ISOBUTYL-PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-ISOBUTYL-PYRIDINE(4810-79-1)
• EPA Substance Registry System: 4-ISOBUTYL-PYRIDINE(4810-79-1)

Safety Data

• Hazardous Substances Data: 4810-79-1(Hazardous Substances Data)

Usage

General Description

4-Isobutyl-pyridine is an organic compound with the chemical formula C10H13N. It is a pyridine derivative with a branched isobutyl group attached to the nitrogen atom. 4-Isobutyl-pyridine has a strong odor and is commonly used as a flavoring ingredient in the food and beverage industry. It is also used as a fragrance ingredient in perfumes and personal care products. Additionally, 4-isobutyl-pyridine has been studied for its potential antimicrobial properties and has been found to have some insecticidal activity. It is important to handle this chemical with care, as it can be harmful if ingested or inhaled and may cause irritation to the skin and eyes.

InChI:InChI=1/C9H13N/c1-8(2)7-9-3-5-10-6-4-9/h3-6,8H,7H2,1-2H3

Upstream product

• 110-86-1 pyridine 
• 97-72-3 2-Methylpropionic anhydride 
• 135351-44-9 2-[2-(2,2-Diethoxy-ethyl)-4-methyl-pentyl]-[1,3]dioxolane 
• 108-89-4 picoline 
• 187737-37-7 propene 
• 6760-50-5 2-methyl-1-(4-pyridyl)-1-propene 
• 135351-40-5 2-(2,2-Diethoxy-ethyl)-2-[1,3]dioxolan-2-ylmethyl-4-methyl-pentanenitrile 
• 135351-36-9 2-(2,2-Diethoxy-ethyl)-4-methyl-pentanenitrile 
• 542-54-1 isocapronitrile 
• 80891-12-9 diisopropyl-1-ethoxycarbonyl-1,4-dihydropyridine-4-phosphonate 
• 882525-03-3 4-(diisopropoxy-phosphoryl)-4-(1-hydroxy-2-methyl-propyl)-4H-pyridine-1-carboxylic acid ethyl ester 
• 75-26-3 isopropyl bromide 
• 75-29-6 isopropyl chloride 

Downstream Products

• 138761-51-0 4-(1-fluoro-2-methylpropyl)pyridine 

Relevant articles and documents

Efficient Diastereoselective Three-Component Synthesis of Pipecolic Amides

An efficient Ugi-type three-component reaction (U-3CR) for the synthesis of pipecolic amides is reported. The U-3CR between electronically diverse isocyanides, carboxylic acids and 4-substituted Δ1-piperideines proceeds in a highly diastereoselective fashion. The Δ1-piperideines are obtained by NCS-mediated oxidation of the corresponding 4-substituted piperidines, which in turn are generated by an efficient two-step procedure involving the alkylation of 4-picoline and subsequent catalytic hydrogenation of the pyridine ring. We demonstrate the utility of this U-3CR, in combination with the convertible isocyanide 2-bromo-6-isocyanopyridine, in the synthesis of the anticoagulant argatroban.

Regioselective synthesis of 4-alkylpyridines from pyridine and aldehydes via dipole reversal process of 1,4-dihydropyridine phosphonate

4-Alkylation of pyridine has been accomplished by the reaction of ylides, derivated from 1,4-dihydropyridine phosphonate via phosphonioalkoxycarbonylation of pyridine with aldehydes and subsequent elimination of diisopropyl phosphate followed by aromatization with potassium tert-butoxide.

LINCOMYCIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY

Novel lincomycin derivatives are disclosed. These lincomycin derivatives exhibit antibacterial activity. As the compounds of the subject invention exhibit potent activities against bacteria, including gram positive organisms, they are useful antimicrobial agents. Methods of synthesis and of use of the compounds are also disclosed.