482-32-6 Usage
Description
6-Methoxy-1,3-dioxolo[4,5-h]furo[2,3-b]quinoline is a furoquinoline alkaloid that has been isolated from the roots of Orixa japonica and also found in the fruit along with skimmianine. This alkaloid is optically inactive and can be converted by Mel at 100°C into isokokusagine, which has a melting point of 247°C. The aurichloride of this compound has a melting point of 171°C, and the picrate has a melting point of 178°C (157°C according to Obata). The structure of this compound has been established by synthesis as 7:8-methylenedioxydictamnine.
Uses
Used in Pharmaceutical Industry:
6-Methoxy-1,3-dioxolo[4,5-h]furo[2,3-b]quinoline is used as a pharmaceutical compound for its potential therapeutic applications. The alkaloid's unique structure and properties make it a promising candidate for the development of new drugs and treatments.
Used in Chemical Research:
In the field of chemical research, 6-Methoxy-1,3-dioxolo[4,5-h]furo[2,3-b]quinoline serves as a valuable compound for studying the properties and reactions of furoquinoline alkaloids. Its synthesis and structural characterization contribute to the understanding of the chemical behavior of similar compounds.
Used in Natural Product Extraction:
6-Methoxy-1,3-dioxolo[4,5-h]furo[2,3-b]quinoline is used in the extraction and isolation of natural products from plants, such as Orixa japonica. This process helps in identifying and characterizing novel bioactive compounds with potential applications in various industries, including pharmaceuticals and cosmetics.
Used in Drug Synthesis:
6-Methoxy-1,3-dioxolo[4,5-h]furo[2,3-b]quinoline is used as a key intermediate in the synthesis of other bioactive molecules and drugs. Its unique structure and properties make it a valuable building block for the development of new pharmaceuticals with improved efficacy and reduced side effects.
Used in Quality Control and Standardization:
6-Methoxy-1,3-dioxolo[4,5-h]furo[2,3-b]quinoline is used as a reference compound for quality control and standardization of natural product extracts. Its well-defined structure and properties allow for accurate quantification and comparison with other compounds, ensuring the consistency and reliability of natural product-based products.
Used in Toxicology Studies:
This furoquinoline alkaloid is used in toxicology studies to evaluate the safety and potential side effects of related compounds. Understanding the toxicological profile of 6-Methoxy-1,3-dioxolo[4,5-h]furo[2,3-b]quinoline can help in the development of safer and more effective drugs based on its structure.
References
Terasaka.,J. Pharm. Soc. Japan, 51,99 (1931)
Obata., ibid, 59,136 (1939)
Structure:
Terasaka et at., Chem. Pharm. Bull. (Tokyo), 2, 159 (1954)
Check Digit Verification of cas no
The CAS Registry Mumber 482-32-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 2 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 482-32:
(5*4)+(4*8)+(3*2)+(2*3)+(1*2)=66
66 % 10 = 6
So 482-32-6 is a valid CAS Registry Number.
482-32-6Relevant articles and documents
Studies on Rutaceae: Part VIII - Chemical Investigation on the Constituents of Atalantia wightii Tanaka, Aegle marmelos Correa ex Koen, Rutea graveolens Linn. and Micromelum pubescens Blume
Banerji, J.,Das, A. K.,Ghoshal, N.,Das, B.
, p. 594 - 596 (2007/10/02)
A new phenolic ester, ethyl p-coumarate (I) and a long chain fatty acid, tetratriacontanoic acid (II) have been obtained from Atalantia wightii Tanaka.Skimmianine (IV) and haplopine (V), two major constituents of Aegle marmelos Corea ex Koen have been tra
