482358-79-2

Basic information

• Product Name: Allyl-{(2R,3S)-3-[(3R,3aS,6aR)-(hexahydro-furo[2,3-b]furan-3-yl)oxycarbonylamino]-2-hydroxy-4-phenyl-butyl}-carbamic acid dec-9-enyl ester
• CAS NO: 482358-79-2
• Molecular Weight: 558.715
• Mol File: 482358-79-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Allyl-{(2R,3S)-3-[(3R,3aS,6aR)-(hexahydro-furo[2,3-b]furan-3-yl)oxycarbonylamino]-2-hydroxy-4-phenyl-butyl}-carbamic acid dec-9-enyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Allyl-{(2R,3S)-3-[(3R,3aS,6aR)-(hexahydro-furo[2,3-b]furan-3-yl)oxycarbonylamino]-2-hydroxy-4-phenyl-butyl}-carbamic acid dec-9-enyl ester(482358-79-2)
• EPA Substance Registry System: Allyl-{(2R,3S)-3-[(3R,3aS,6aR)-(hexahydro-furo[2,3-b]furan-3-yl)oxycarbonylamino]-2-hydroxy-4-phenyl-butyl}-carbamic acid dec-9-enyl ester(482358-79-2)

Safety Data

• Hazardous Substances Data: 482358-79-2(Hazardous Substances Data)

Upstream product

• 253265-97-3 1-[[[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yloxy]carbonyl]oxy]pyrrolidine-2,5-dione 
• 482358-77-0 Allyl-((2R,3S)-3-amino-2-hydroxy-4-phenyl-butyl)-carbamic acid dec-9-enyl ester 
• 13019-22-2 9-Decen-1-ol 
• 482358-73-6 (2R,3S)-1-Allylamino-3-azido-4-phenyl-butan-2-ol 
• 205761-19-9 Carbonic acid dec-9-enyl ester 2,5-dioxo-pyrrolidin-1-yl ester 
• 136465-89-9 (2S)-2-[1'(S)-1-azido-2-phenylethyl]oxirane 

Downstream Products

• 482358-81-6 [(1S,2R)-1-Benzyl-2-hydroxy-3-((Z)-2-oxo-1-oxa-3-aza-cyclotetradec-5-en-3-yl)-propyl]-carbamic acid (3R,3aS,6aR)-(hexahydro-furo[2,3-b]furan-3-yl) ester 

Relevant articles and documents

Novel cyclourethane-derived HIV protease inhibitors: A ring-closing olefin metathesis based strategy

A series of novel macrocyclic urethanes incorporating a (R)-hydroxyethylamine isostere was designed and synthesized. Ring size and substituent efffects have been investigated. Cyclourethanes containing 14- to 16-membered rings exhibited low nanomolar inhibitory potencies against HIV-1 protease.