482577-59-3 Usage
Description
L-VALINE, N-[(2'-CYANO[1,1'-BIPHENYL]-4-YL)METHYL]-, METHYL ESTER, MONOHYDROCHLORIDE is a chemical compound with a complex structure, characterized by its cyano and biphenyl components. It is an ester derivative of L-valine, a naturally occurring amino acid, and is further modified with a methyl ester and hydrochloride salt. L-VALINE, N-[(2'-CYANO[1,1'-BIPHENYL]-4-YL)METHYL]-, METHYL ESTER, MONOHYDROCHLORIDE is known for its potential applications in the pharmaceutical industry.
Uses
Used in Pharmaceutical Industry:
L-VALINE, N-[(2'-CYANO[1,1'-BIPHENYL]-4-YL)METHYL]-, METHYL ESTER, MONOHYDROCHLORIDE is used as an intermediate in the preparation of angiotensin II type 1 receptor antagonists. These antagonists are important for the development of medications that help regulate blood pressure and treat conditions related to the renin-angiotensin system, such as hypertension and heart failure.
Check Digit Verification of cas no
The CAS Registry Mumber 482577-59-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,2,5,7 and 7 respectively; the second part has 2 digits, 5 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 482577-59:
(8*4)+(7*8)+(6*2)+(5*5)+(4*7)+(3*7)+(2*5)+(1*9)=193
193 % 10 = 3
So 482577-59-3 is a valid CAS Registry Number.
482577-59-3Relevant articles and documents
A method for preparing methyl valsartan
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Paragraph 0055-0056, (2017/08/25)
The invention provides a preparation method of valsartan. The preparation method has the technical effects that amide methyl ester and sodium azide are used as raw materials and are catalyzed by amine salt to carry out tetrazole formation reaction; side effects are minimized by controlling the reaction course; main products are furthest generated; unreacted raw materials are recycled and reused; the yield in the preparation method is increased by more than 10% relative to the yields in existing processes; compared with the existing processes, the method has the effect that plenty of high-toxicity wastewater is no longer generated, and is easy to be widely popularized industrially.