483-19-2 Usage
Description
Emetamine, also known as emetine, is a pyridoisoquinoline alkaloid derived from plants in the ipecac genus, particularly Cephaelis ipecacuanha. It is a fully aromatized isoquinoline with various pharmacological properties and applications.
Uses
Used in Pharmaceutical Industry:
Emetamine is used as a pharmaceutical agent for its emetic and expectorant properties. It has been traditionally used to induce vomiting in cases of poisoning or as an aid in the treatment of certain respiratory conditions due to its ability to stimulate the secretion of mucus.
Used in Research Applications:
In the field of research, emetamine is utilized as a tool to study the mechanisms of protein synthesis and cellular processes. Its ability to inhibit the 60S ribosomal subunit has made it a valuable compound for understanding the translation process in cells.
Used in Traditional Medicine:
Emetamine has been employed in traditional medicine for its various therapeutic properties. It has been used to treat conditions such as dysentery, amoebic infections, and certain skin diseases, although its use in modern medicine has been limited due to its potential toxicity.
Check Digit Verification of cas no
The CAS Registry Mumber 483-19-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 3 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 483-19:
(5*4)+(4*8)+(3*3)+(2*1)+(1*9)=72
72 % 10 = 2
So 483-19-2 is a valid CAS Registry Number.
InChI:InChI=1/C29H36N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h7,9,13-16,18,21,25H,6,8,10-12,17H2,1-5H3/t18-,21-,25-/m0/s1
483-19-2Relevant articles and documents
Synthesis of 2,3-cis stereomeric emetamines via Reissert compounds
Reimann, Eberhard,Renz, Manfred
, p. 211 - 218 (2008/02/01)
Alkylation of Reissert compounds with certain benzoquinolizinone derivatives followed by hydrolytic cleavage afforded the core of the title compounds in a two step sequence. Finally, the lactam intermediates were reduced with DIBAH giving the target compo
