4836-69-5Relevant articles and documents
New photolabile protecting groups in nucleoside and nucleotide chemistry - Synthesis, cleavage mechanisms and applications
Giegrich,Eisele-Buehler,Hermann,Kvasyuk,Charubala,Pfleiderer
, p. 1987 - 1996 (2007/10/03)
New photolabile protecting groups have been found in the 2-(2- nitrophenyl)ethoxycarbonyl and the 2-(2-nitrophenyl)ethylsulfonyl group, respectively. The influence of substituents at the phenyl ring as well as the side-chain has been investigated regarding the photolysis rates on irradiation at 365 mn. β-Branching in the side-chain leads to highly increased rates of photodeprotection. A new type of photocleavage mechanism consisting of a photoinduced β-elimination process is proposed.
S-2-(2,4-dinitrophenyl)ethyl-L-cysteine: A new derivative for solid-phase peptide synthesis
Royo,Garcia-Echeverria,Giralt,Eritja,Albericio
, p. 2391 - 2394 (2007/10/02)
A new acid stable protecting group for the sulfhydryl function of cysteine is described. The S-2-(2,4-dinitrophenyl)ethyl-L-cysteine derivative is fully compatible with the Boc/Bzl solid-phase peptide synthesis strategy and can be smoothly and quantitatively removed to give the free thiol or a disulfide bridge.