4837-20-1 Usage
Description
4-(Difluoromethoxy)benzoic acid is a chemical compound characterized by the presence of a difluoromethoxy group at the para position of the benzene ring in the benzoic acid structure. This modification introduces unique properties to the molecule, making it suitable for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
4-(Difluoromethoxy)benzoic acid is used as an intermediate in the synthesis of pharmaceutical compounds for [application reason]. Its specific structural features allow for the development of new drugs with potential therapeutic benefits.
Used in Chemical Synthesis:
In the chemical industry, 4-(Difluoromethoxy)benzoic acid is used as a building block for the creation of more complex molecules with specific functions, such as [application reason]. Its reactivity and structural properties make it a valuable component in the synthesis of various chemical products.
Used in Material Science:
4-(Difluoromethoxy)benzoic acid can be utilized in the development of novel materials with tailored properties, such as [application reason]. Its incorporation into polymers or other materials can lead to improved performance characteristics, making it a valuable addition to the field of material science.
Used in Research and Development:
As a versatile chemical compound, 4-(Difluoromethoxy)benzoic acid is also used in research and development for [application reason]. Its unique properties make it an interesting candidate for exploring new reactions, mechanisms, and potential applications in various scientific fields.
Check Digit Verification of cas no
The CAS Registry Mumber 4837-20-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,8,3 and 7 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 4837-20:
(6*4)+(5*8)+(4*3)+(3*7)+(2*2)+(1*0)=101
101 % 10 = 1
So 4837-20-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H6F2O3/c9-8(10)13-6-3-1-5(2-4-6)7(11)12/h1-4,8H,(H,11,12)/p-1
4837-20-1Relevant articles and documents
DIFLUOROMETHOXYLATION AND TRIFLUOROMETHOXYLATION COMPOSITIONS AND METHODS FOR SYNTHESIZING SAME
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Page/Page column 75; 79; 89; 102-103, (2019/09/18)
The present invention provides a compound having the structure (I), a processing of making the compound; and a process of using the compound as a reagent for the difluoromethoxylation and trifluoromethoxylation of arenes or heteroarenes.
Catalytic radical difluoromethoxylation of arenes and heteroarenes
Lee, Johnny W.,Zheng, Weijia,Morales-Rivera, Cristian A.,Liu, Peng,Ngai, Ming-Yu
, p. 3217 - 3222 (2019/03/21)
Intermolecular C-H difluoromethoxylation of (hetero)arenes remains a long-standing and unsolved problem in organic synthesis. Herein, we report the first catalytic protocol employing a redox-active difluoromethoxylating reagent 1a and photoredox catalysts for the direct C-H difluoromethoxylation of (hetero)arenes. Our approach is operationally simple, proceeds at room temperature, and uses bench-stable reagents. Its synthetic utility is highlighted by mild reaction conditions that tolerate a wide variety of functional groups and biorelevant molecules. Experimental and computational studies suggest single electron transfer (SET) from excited photoredox catalysts to 1a forming a neutral radical intermediate that liberates the OCF2H radical exclusively. Addition of this radical to (hetero)arenes gives difluoromethoxylated cyclohexadienyl radicals that are oxidized and deprotonated to afford the products of difluoromethoxylation.
