484-29-7 Usage
Description
DICTAMNINE, also known as Dictamnine, is a natural alkaloid derived from the root of Dictamnus dasycarpus, a plant commonly found in Asia. It possesses a variety of biological activities, including antifungal, vasal relaxant, and smooth muscle contractant properties. These characteristics make DICTAMNINE a versatile compound with potential applications in various industries.
Uses
Used in Pharmaceutical Industry:
DICTAMNINE is used as an antifungal agent for its ability to inhibit the growth of fungi, making it a potential candidate for the development of antifungal medications.
DICTAMNINE is used as a vasal relaxant for its ability to relax blood vessels, which can be beneficial in treating conditions related to vascular constriction.
DICTAMNINE is used as a smooth muscle contractant for its ability to cause contraction in smooth muscles, which can be useful in various therapeutic applications.
Used in Agricultural Industry:
DICTAMNINE is used as a phytotoxic agent for its ability to exhibit anti-microbial activity against bacteria and fungi, making it a potential candidate for the development of biopesticides and other plant protection products.
Synthesis Reference(s)
Tetrahedron Letters, 14, p. 843, 1973 DOI: 10.1016/S0040-4039(01)95731-4
Check Digit Verification of cas no
The CAS Registry Mumber 484-29-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 4 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 484-29:
(5*4)+(4*8)+(3*4)+(2*2)+(1*9)=77
77 % 10 = 7
So 484-29-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H9NO2/c1-14-11-8-4-2-3-5-10(8)13-12-9(11)6-7-15-12/h2-7H,1H3
484-29-7Relevant articles and documents
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Boulanger et al.
, p. 2399,2404 (1973)
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Monkovic,Spenser
, p. 204 (1966)
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Tuppy,Boehm
, p. 735,738 (1956)
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Biphenyl dioxygenase-catalysed cis-dihydroxylation of tricyclic azaarenes: Chemoenzymatic synthesis of arene oxide metabolites and furoquinoline alkaloids
Boyd, Derek R.,Sharma, Narain D.,Carroll, Jonathan G.,Loke, Pui L.,O'Dowd, Colin R.,Allen, Christopher C. R.
, p. 10944 - 10955 (2013/09/02)
Biotransformation of acridine, dictamnine and 4-chlorofuro[2,3-b]quinolone, using whole cells of Sphingomonas yanoikuyae B8/36, yielded five enantiopure cyclic cis-dihydrodiols, from biphenyl dioxygenase-catalysed dihydroxylation of the carbocyclic rings.
Synthesis of (+)-myrtopsine, (+)-7,8-dimethoxymyrtopsine, and related 2,3-dihydro-3-hydroxy-2-(1-hydroxy-1-methyl-ethyl)benzofuran natural products
Snider, Barry B.,Wu, Xiaoxing
, p. 279 - 294 (2008/04/18)
The first syntheses of myrtopsine (8t) and 7,8-dimethoxymyrtopsine (9t) have been carried out by halogen-metal exchange of 3-iodo-4-methoxy-quinolin-2(1H)-ones (15) and (21) with i-PrMgCl followed by addition of 3,3-dimethyloxirane-2-carboxaldehyde (1). A two-step sequence leads selectively to trans-2,3-dihydro-3-hydroxy-2-(1-hydroxy-1-methylethyl)benzofurans (7t), (8t), (9t), (28), and (32) by conversion of a 2-iodophenol or a 3-iodo-4-methoxyquinolin-2(1H)-one to an aryl Grignard reagent and addition of 3-methyl-2-butenal, followed by threo selective epoxidation of the resulting allylic alcohol and cyclization with inversion.
