484-43-5 Usage
Description
ASP-ARG-VAL-TYR-VAL-HIS-PRO-PHE-HIS-LEU, also known as Angiotensin I, is a peptide derived from the renin-angiotensin system. It is a precursor to angiotensin II and angiotensin fragment 1-7, which play crucial roles in the regulation of fluid volume and the release of aldosterone. Angiotensin I is considered a putative neurotransmitter and is involved in various physiological processes.
Uses
Used in Pharmaceutical Industry:
ASP-ARG-VAL-TYR-VAL-HIS-PRO-PHE-HIS-LEU is used as a therapeutic agent for the treatment of hypertension and heart failure. It is involved in the regulation of blood pressure and fluid balance in the body, making it a potential target for drug development.
Used in Research and Development:
ASP-ARG-VAL-TYR-VAL-HIS-PRO-PHE-HIS-LEU is used as a research tool for studying the renin-angiotensin system and its role in various physiological processes. It helps researchers understand the mechanisms underlying blood pressure regulation, fluid balance, and the release of aldosterone.
Used in Diagnostic Applications:
ASP-ARG-VAL-TYR-VAL-HIS-PRO-PHE-HIS-LEU can be used as a biomarker for the diagnosis of certain cardiovascular and renal diseases. Its involvement in the renin-angiotensin system makes it a potential indicator for conditions related to blood pressure regulation and fluid balance.
Used in Drug Delivery Systems:
Similar to gallotannin, ASP-ARG-VAL-TYR-VAL-HIS-PRO-PHE-HIS-LEU can be incorporated into drug delivery systems to improve its bioavailability and therapeutic outcomes. These systems can be tailored to enhance the peptide's delivery to specific target tissues, increasing its efficacy in treating related conditions.
Used in Anticancer Applications:
While not explicitly mentioned in the provided materials, ASP-ARG-VAL-TYR-VAL-HIS-PRO-PHE-HIS-LEU could potentially be investigated for its role in cancer research, given its involvement in various physiological processes. Further studies may reveal its potential as an anticancer agent or a modulator of cancer-related signaling pathways.
Check Digit Verification of cas no
The CAS Registry Mumber 484-43-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 4 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 484-43:
(5*4)+(4*8)+(3*4)+(2*4)+(1*3)=75
75 % 10 = 5
So 484-43-5 is a valid CAS Registry Number.
InChI:InChI=1/C61H87N17O14/c1-32(2)22-40(62)51(82)71-43(25-37-28-65-30-68-37)53(84)74-45(24-35-12-8-7-9-13-35)59(90)78-21-11-15-47(78)56(87)72-44(26-38-29-66-31-69-38)55(86)77-50(34(5)6)58(89)73-42(23-36-16-18-39(79)19-17-36)54(85)76-49(33(3)4)57(88)70-41(14-10-20-67-61(63)64)52(83)75-46(60(91)92)27-48(80)81/h7-9,12-13,16-19,28-34,40-47,49-50,79H,10-11,14-15,20-27,62H2,1-6H3,(H,65,68)(H,66,69)(H,70,88)(H,71,82)(H,72,87)(H,73,89)(H,74,84)(H,75,83)(H,76,85)(H,77,86)(H,80,81)(H,91,92)(H4,63,64,67)/t40-,41-,42-,43-,44-,45-,46-,47-,49-,50-/m0/s1
