4846-19-9 Usage
Description
(R)-Nornuciferine, an alkaloid derived from Hottuynia cordata, is a bioactive compound with significant pharmacological properties. It is characterized by its potential anti-inflammatory activity and is a promising candidate for various therapeutic applications.
Uses
Used in Pharmaceutical Industry:
(R)-Nornuciferine is used as a therapeutic agent for its anti-inflammatory properties, which can be beneficial in the treatment of various inflammatory conditions and diseases. Its natural origin and potential to modulate immune responses make it a valuable addition to the pharmaceutical sector.
Used in Nutraceutical Applications:
In the nutraceutical industry, (R)-Nornuciferine can be utilized as an ingredient in dietary supplements and functional foods due to its anti-inflammatory and potential health-promoting benefits. Its incorporation into these products may contribute to overall wellness and support a healthy immune system.
Used in Cosmetics and Personal Care:
(R)-Nornuciferine's anti-inflammatory properties can also be harnessed in the cosmetics and personal care industry. It may be used as an active ingredient in skincare products, targeting inflammation-related skin conditions such as acne, rosacea, or eczema, and promoting a healthier skin appearance.
Used in Research and Development:
As a bioactive compound with potential therapeutic applications, (R)-Nornuciferine is valuable in research and development for the discovery of new drugs and therapies. Its study can lead to a better understanding of its mechanisms of action and the development of novel treatments for various health conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 4846-19-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,8,4 and 6 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 4846-19:
(6*4)+(5*8)+(4*4)+(3*6)+(2*1)+(1*9)=109
109 % 10 = 9
So 4846-19-9 is a valid CAS Registry Number.
4846-19-9Relevant articles and documents
Stereoselective total synthesis of (S)- and (R)-nuciferine using benzyne chemistry
Casagrande, Gleison A.,Deflon, Victor M.,Martins, Gabriel R.,Oliveira-Silva, Diogo,Perecim, Givago P.,Pinto, Leandro M. C.,Raminelli, Cristiano
, (2020/08/13)
Total syntheses of (S)- and (R)-nuciferine were accomplished through approach involving diastereoselective reaction between a chiral dihydroisoquinoline enamide and 2-(trimethylsilyl)phenyl trifluoromethanesulfonate promoted by CsF, affording a separable mixture of diastereoisomers, which provided (S)- and (R)-nuciferine via simple and efficient transformations.
Aporphine alkaloid synthesis and diversification via direct arylation
Lafrance, Marc,Blaquiere, Nicole,Fagnou, Keith
, p. 811 - 825 (2008/02/12)
Palladium-catalyzed direct arylation of aryl chlorides, bromides and iodides has been applied to the preparation of new aporphine analogues including C2-substituted aporphines by reaction with benzodioxole, pyridine N-oxide and pyrazine N-oxide. Successful application of direct arylation in these diversification reactions highlights its utility not only in convergent, but also in divergent synthesis. We also describe enantioselective syntheses of (R)-nornuciferine and (R)-nuciferine employing a catalytic asymmetric transfer hydrogenation in high yield and excellent enantiomeric excess. Wiley-VCH Verlag GmbH & Co. KGaA, 2007.
