485334-41-6

Basic information

• Product Name: 2-(4-ethyl-5-phenyl-4H-[1,2,4]triazol-3-ylsulfanyl)-1-phenylethanone
• Synonyms: 2-(4-ethyl-5-phenyl-4H-[1,2,4]triazol-3-ylsulfanyl)-1-phenylethanone
• CAS NO: 485334-41-6
• Molecular Weight: 323.418
• Mol File: 485334-41-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4-ethyl-5-phenyl-4H-[1,2,4]triazol-3-ylsulfanyl)-1-phenylethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-ethyl-5-phenyl-4H-[1,2,4]triazol-3-ylsulfanyl)-1-phenylethanone(485334-41-6)
• EPA Substance Registry System: 2-(4-ethyl-5-phenyl-4H-[1,2,4]triazol-3-ylsulfanyl)-1-phenylethanone(485334-41-6)

Safety Data

• Hazardous Substances Data: 485334-41-6(Hazardous Substances Data)

Upstream product

• 613-94-5 benzoic acid hydrazide 
• 93-89-0 benzoic acid ethyl ester 
• 26131-61-3 3-mercapto-4-ethyl-5-phenyl-1,2,4-triazole 
• 70-11-1 α-bromoacetophenone 
• 65-85-0 benzoic acid 
• 26257-93-2 2-benzoyl-N-ethylhydrazinecarbothioamide 

Relevant articles and documents

New nitric oxide donating 1,2,4-triazole/oxime hybrids: Synthesis, investigation of anti-inflammatory, ulceroginic liability and antiproliferative activities

A series of novel nitric oxide (NO) donating triazole/oxime hybrids was prepared and evaluated for their anti-inflammatory activity. Most of the tested compounds showed significant anti-inflammatory activity using carrageenan-induced rat paw edema method compared to indomethacin. Calculation of the ulcer indices and histopathological investigation indicated that the prepared NO-donating oximes exhibited less ulcerogenicity compared to their intermediate ketones and indomethacin. The NO-donating oxime 6i revealed significant activity against renal cancer A498 cell lines with 50.52 cell growth inhibition.