485820-12-0

Basic information

• Product Name: (R)-3-N-BOC-AMINO-1-CBZ-PIPERIDINE
• Synonyms: (R)-3-N-BOC-AMINO-1-CBZ-PIPERIDINE;(3R)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-piperidinecarboxylic acid phenylmethyl ester;Benzyl (3R)-3-[(tert-butoxycarbonyl)amino]piperidine-1-carboxylate;(R)-1-Cbz-3-(Boc-aMino)piperidine;(R)-1-Cbz-3-N-Boc-aMinopiperidine;(R)-Benzyl 3-((Tert-Butoxycarbonyl)Amino)Piperidine-1-Carboxylate
• CAS NO: 485820-12-0
• Molecular Formula: C₁₈H₂₆N₂O₄
• Molecular Weight: 334.41
• Mol File: 485820-12-0.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 471.9±44.0 °C(Predicted)
• Appearance: /
• Density: 1.15
• Storage Temp.: 2-8°C
• PKA: 12.25±0.20(Predicted)
• CAS DataBase Reference: (R)-3-N-BOC-AMINO-1-CBZ-PIPERIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-N-BOC-AMINO-1-CBZ-PIPERIDINE(485820-12-0)
• EPA Substance Registry System: (R)-3-N-BOC-AMINO-1-CBZ-PIPERIDINE(485820-12-0)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-37
• Hazardous Substances Data: 485820-12-0(Hazardous Substances Data)

Usage

General Description

The chemical compound (R)-3-N-BOC-AMINO-1-CBZ-PIPERIDINE is a derivative of piperidine, a six-membered heterocyclic ring containing five carbon atoms and one nitrogen atom. The compound contains a BOC (tert-butyloxycarbonyl) protecting group on the amine group at position 3, and a CBZ (carboxybenzyl) protecting group on the amine group at position 1. These protecting groups are commonly used in organic synthesis to prevent unwanted reactions at specific functional groups. (R)-3-N-BOC-AMINO-1-CBZ-PIPERIDINE has potential applications in peptide and drug synthesis, as well as in the development of novel pharmaceutical compounds due to its versatile reactivity and functional group compatibility.

Upstream product

• 1050446-94-0 C₁₄H₁₈N₂O₃ 
• 78190-11-1 1-benzyloxycarbonylpiperidine-3-carboxylic acid 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1044560-96-4 (R)-benzyl 3-aminopiperidine-1-carboxylate 
• 309956-78-3 (R)-piperidin-3-ylcarbamic acid tert-butyl ester 
• 501-53-1 benzyl chloroformate 
• 160706-62-7 (R)-1-((benzyloxy)carbonyl)piperidine-3-carboxylic acid 

Downstream Products

• 1044560-96-4 (R)-benzyl 3-aminopiperidine-1-carboxylate 
• 1196506-95-2 tert-butyl N-ethyl-N-(3-piperidyl)carbamate 
• 309962-67-2 methyl (R)-piperidin-3-ylcarbamic acid tert-butyl ester 
• 1196506-93-0 (R)-benzyl 3-(tert-butoxycarbonyl(ethyl)amino)piperidine-1-carboxylate 
• 1124199-23-0 (R)-benzyl 3-(tert-butoxycarbonyl(methyl)amino)piperidine-1-carboxylate 
• 309956-78-3 (R)-piperidin-3-ylcarbamic acid tert-butyl ester 

Relevant articles and documents

METALLO-BETA-LACTAMASE INHIBITORS AND METHODS OF USE THEREOF

The present invention relates to metallo-β-lactamase inhibitor compounds of Formula (I) and pharmaceutically acceptable salts thereof, wherein Z, RA, X1, X2 and R1 are as defined herein. The present invention also relates to compositions which comprise a metallo-β-lactamase inhibitor compound of the invention or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, optionally in combination with a beta lactam antibiotic and/or a beta-lactamase inhibitor. The invention further relates to methods for treating a bacterial infection comprising administering to a patient a therapeutically effective amount of a compound of the invention, in combination with a therapeutically effective amount of one or more β-lactam antibiotics and optionally in combination with one or more beta-lactamase inhibitor compounds. The compounds of the invention are useful in the methods described herein for overcoming antibiotic resistance.

A as dipeptidyl peptidase -4 inhibitor for the preparation of compounds of the

The invention relates to a preparation method of a biguanide derivative as a dipeptidyl peptidase-4 inhibitor (DPP-IV). The biguanide derivative can be used for treating all symptoms or diseases benefited by inhibiting the activity of DPP-IV, for example type 1 and 2 diabetes, diabetic complication and other related diseases.

A as dipeptidyl peptidase -4 inhibitor compounds

The invention relates to a compound as a dipeptidyl peptidase-4 (DPP-IV) inhibitor, which can be used for treating all symptoms or diseases that get benefits by inhibiting DPP-IV activity, such as type I and II diabetes, diabetes complications and other related diseases.