486999-96-6

Basic information

• Product Name: 1H-Imidazole, 2-iodo-1-(phenylethynyl)-
• CAS NO: 486999-96-6
• Molecular Formula: C11H7IN2
• Molecular Weight: 294.094
• Mol File: 486999-96-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1H-Imidazole, 2-iodo-1-(phenylethynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Imidazole, 2-iodo-1-(phenylethynyl)-(486999-96-6)
• EPA Substance Registry System: 1H-Imidazole, 2-iodo-1-(phenylethynyl)-(486999-96-6)

Safety Data

• Hazardous Substances Data: 486999-96-6(Hazardous Substances Data)

Upstream product

• 1046136-03-1 1-(2-phenylethynyl)-1H-imidazole 
• 3034-62-6 2-iodo-1H-imidazole 
• 130410-08-1 phenyl(phenylethynyl)iodonium triflate 
• 79069-32-2 phenyl(phenylethynyl)iodonium tosylate 

Downstream Products

• 486999-99-9 2-ethynyl-1-(phenylethynyl)-1H-imidazole 
• 486999-98-8 1-phenylethynyl-2-[(triisopropylsilanyl)-ethynyl]imidazole 
• 69214-21-7 5-chloro-8-phenyl-imidazo[1,2-a]pyridine 
• 887601-41-4 C₁₃H₇⁽²⁾HN₂ 

Relevant articles and documents

Lithiation and functionalization of 1-alkynylimidazoles at the 2-position

Functionalization reactions of 1-alkynylimidazoles involving the formation of their 2-lithio derivatives followed by addition of various electrophiles are presented. This allows access to previously unreported 1,2-dialkynylimidazoles via 1-alkynyl-2-iodoi

Intra- and intermolecular trapping of cyclopentapyrazine carbenes derived from 1,2-dialkynylimidazoles

The thermolysis of 1,2-dialkynylimidazoles in benzene solution affords high yields of 7-phenyl-5H-cyclopentapyrazines, which presumably form by solvent trapping of cyclopentapyrazine carbene intermediates. In cases where dialkynylimidazole contains side chains that can participate in intramolecular carbene C-H insertion or olefin addition, these processes compete with solvent addition to afford novel tri- and tetracyclic pyrazines, which can be obtained in good yield when the thermolysis is carried out in hexafluorobenzene.