487-42-3 Usage
Description
(3Z)-3-(phenylimino)-2-benzofuran-1(3H)-one is a heterocyclic compound characterized by the presence of a benzofuran ring and a phenylimino group. It is recognized as the Schiff base derived from the condensation of 2-benzofuran-1(3H)-one and aniline. (3Z)-3-(phenylimino)-2-benzofuran-1(3H)-one is notable for its potential applications in various fields due to its unique structural features and biological activities.
Uses
Used in Pharmaceutical Development:
(3Z)-3-(phenylimino)-2-benzofuran-1(3H)-one serves as a valuable scaffold in the pharmaceutical industry due to its demonstrated biological activities. It is used as a precursor in the synthesis of new pharmaceuticals and biologically-active compounds, leveraging its antimicrobial, antitumor, and antioxidant properties for the development of innovative treatments.
Used in Organic Synthesis:
In the field of organic chemistry, (3Z)-3-(phenylimino)-2-benzofuran-1(3H)-one is utilized as a building block for the preparation of a diverse range of organic molecules. Its unique structure allows for the creation of complex organic compounds, making it an essential component in advanced organic synthesis processes.
Used in Antimicrobial Applications:
(3Z)-3-(phenylimino)-2-benzofuran-1(3H)-one is employed as an antimicrobial agent, capitalizing on its ability to combat various microorganisms. This application is particularly relevant in the development of new antibiotics and antifungal agents, addressing the growing need for effective treatments against drug-resistant pathogens.
Used in Antitumor Research:
(3Z)-3-(phenylimino)-2-benzofuran-1(3H)-one is also used in antitumor research, where its potential to inhibit tumor growth and proliferation is explored. (3Z)-3-(phenylimino)-2-benzofuran-1(3H)-one may contribute to the development of novel anticancer drugs, offering new therapeutic options for cancer patients.
Used in Antioxidant Formulations:
Leveraging its antioxidant properties, (3Z)-3-(phenylimino)-2-benzofuran-1(3H)-one is used in the development of antioxidant formulations. These can be incorporated into various products, such as dietary supplements, cosmetics, and pharmaceuticals, to provide protection against oxidative stress and related conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 487-42-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 7 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 487-42:
(5*4)+(4*8)+(3*7)+(2*4)+(1*2)=83
83 % 10 = 3
So 487-42-3 is a valid CAS Registry Number.
487-42-3Relevant articles and documents
Isoimides of benzene-1,2-dicarboxylic acid and napthalene-1,8-dicarboxylic acid. Suitable conditions for preparation
Ganin
, p. 1092 - 1094 (1997)
N-Arylisophthalimides are formed in an aprotic solvent at 20°C from equivalent quantities of phthaloyl chloride and an arylamine in the presence of not less than 1 mole of a dehydrochlorinating reagent. N-Nitrophenylisonaphthalimides were obtained by the
The reaction of phthalidylidene dichloride with primary amines. Synthesis and X-ray molecular structure of N-substituted phthalisoimides
Guirado, Antonio,Zapata, Andres,Ramirez De Arellano, M. Carmen
, p. 5305 - 5324 (2007/10/03)
An efficient method for the synthesis of N-substituted phthalisoimides, by reaction of phthalidylidene dichloride with primary amines, is described. The reactions with arylamines, arylenediamincs and alkylenediamines lead to the corresponding phthalisoimides or bisphthalisoimides in nearly quantitative yields. However, the reactions with alkylamines are not useful because of the relatively high nucleophilicity of alkylamines. Certain particular behaviours of arylamines, associated with the presence of specific ortho-substituents have been found. The reactions of arylamines bearing an o-hydroxymethyl group provide a convenient method for preparing 2-benzoxazinylbenzoic acids. The X-ray crystallographic structures of N-(2-methoxyphenyl)phthalisoimide 3a and 2-(4H-3.1-benzoxazin-2-yl)benzoic acid 15a have been determined.
A NEW METHOD FOR THE SYNTHESIS OF N-ARYLPHTHALISOIMIDES
Guirado, Antonio,Zapata, Andres,Fenor, Manuel
, p. 2633 - 2636 (2007/10/02)
N-arylphthalisoimides have been synthesized in almost quantitative yields by the reaction, under very mild conditions, of 3,3-dichlorphthalide with aromatic amines.
