4883-72-1 Usage
Description
N-CYCLOHEXYL-N-NITROSOHYDROXYLAMINE, also known as N-Nitroso N-Hydroxy Cyclohexanamine, is a chemical compound derived from Cyclohexanone (C987980). It is an intermediate in the synthesis of CCNU, a potent antitumor agent. N-CYCLOHEXYL-N-NITROSOHYDROXYLAMINE plays a crucial role in the development of effective cancer treatments.
Uses
Used in Pharmaceutical Industry:
N-CYCLOHEXYL-N-NITROSOHYDROXYLAMINE is used as an intermediate in the synthesis of CCNU for its role in creating an effective antitumor agent. N-CYCLOHEXYL-N-NITROSOHYDROXYLAMINE contributes to the development of cancer treatments by being a part of the process that leads to the production of CCNU, which has demonstrated its ability to combat various types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 4883-72-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,8,8 and 3 respectively; the second part has 2 digits, 7 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4883-72:
(6*4)+(5*8)+(4*8)+(3*3)+(2*7)+(1*2)=121
121 % 10 = 1
So 4883-72-1 is a valid CAS Registry Number.
4883-72-1Relevant articles and documents
An efficient synthesis of: N -nitrosamines under solvent, metal and acid free conditions using tert -butyl nitrite
Chaudhary, Priyanka,Gupta, Surabhi,Muniyappan, Nalluchamy,Sabiah, Shahulhameed,Kandasamy, Jeyakumar
, p. 2323 - 2330 (2016/05/19)
Synthesis of various N-nitroso compounds from secondary amines is reported using tert-butyl nitrite (TBN) under solvent free conditions. Broad substrate scope, metal and acid free conditions, easy isolation procedure and excellent yields are few important features of this methodology. The acid labile protecting groups such as tert-butyldimethylsilyl (TBDMS) and tert-butyloxycarbonyl (Boc) as well as sensitive functional groups such as phenols, olefins and alkynes are found to be stable under the standard reaction conditions. Besides N-nitrosation, TBN is also found to be an efficient reagent in few other transformations including aryl hydrazines to aryl azides and primary amides to carboxylic acids under mild conditions.
