4885-07-8

Basic information

• Product Name: ((but-2-yn-1-yloxy)methyl)benzene
• Synonyms: ((but-2-yn-1-yloxy)methyl)benzene
• CAS NO: 4885-07-8
• Molecular Weight: 160.216
• Mol File: 4885-07-8.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: ((but-2-yn-1-yloxy)methyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: ((but-2-yn-1-yloxy)methyl)benzene(4885-07-8)
• EPA Substance Registry System: ((but-2-yn-1-yloxy)methyl)benzene(4885-07-8)

Safety Data

• Hazardous Substances Data: 4885-07-8(Hazardous Substances Data)

Upstream product

• 689-97-4 3-buten-1-yne 
• 100-51-6 benzyl alcohol 
• 4039-82-1 Benzyl propargyl ether 
• 5633-34-1 (benzoylmethylene)dimethylsulfurane 
• 764-01-2 methyl propargyl alcohol 
• 100-39-0 benzyl bromide 
• 10323-20-3 D-Arabinose 
• 135697-04-0 (((4-bromobut-2-yn-1-yl)oxy)methyl)benzene 
• 100-44-7 benzyl chloride 
• 3355-28-0 1-Bromo-2-butyne 

Downstream Products

• 791845-45-9 (Z)-4,4,5,5-tetramethyl-2-(1-methyl-3-phenylmethoxy-1-propenyl)-1,3,2-dioxaborolane 
• 1379681-11-4 C₁₇H₂₅BO₃ 
• 104306-94-7 2-benzyloxymethyl-but-2-en-1-ol 
• 93877-21-5 1,4-dibenzyloxybut-2-yne 
• 27299-31-6 (Z)-((but-2-en-1-yloxy)methyl)benzene 
• 1533453-04-1 3-((benzyloxy)methyl)-1-phenylpent-4-en-1-one 
• 70388-33-9 4-benzyloxybut-1-ene 

Relevant articles and documents

A Chan-Evans-Lam approach to trisubstituted vinyl ethers

Trisubstituted vinyl ethers were accessedviaChan-Evans-Lam coupling of vinyl trifluoroborates and primary aliphatic alcohols. This approach complements prior methods that required the use of neat liquid alcohol coupling partners. A palladium-catalyzed redox-relay Heck reaction was used to convert several vinyl ethers into aldehyde-functionalized 1,3-dihydroisobenzofurans.

Palladium-catalyzed methylation of alkynyl C(sp)-H bonds with dimethyl sulfonium ylides

A novel palladium-catalyzed methylation protocol for the synthesis of methyl-functionalized internal alkynes has been established. This methylation method is achieved through a C(sp)-C(sp3) bond formation process and represents a new synthetic application of sulfonium ylides.

Indium-mediated allenylation of aldehydes and its application in carbohydrate chemistry: Efficient synthesis of D -ribulose and 1-deoxy- D -ribulose

A two-step reaction sequence starting with the indium-mediated allenylation of aldehydes with 4-bromo-2-butyn-1-ols and subsequent ozonolysis of the resulting allenylic product was developed to generate a variety of dihydroxyacetone derivatives. The regioselectivity of the indium-promoted C-C bond-forming reaction can be manipulated through hydroxy protecting groups on 4-bromo-2-butyn-1-ol, yielding either allenes or alkynes as preferred products. Compared to established protocols, the necessary amount of indium for this type of allenylation can be decreased by a factor of two to four. The versatility of this strategy was demonstrated in thestereoselective and straightforward synthesis of D-ribulose and 1-deoxy-D-ribulose. Copyright