489-85-0

Basic information

• Product Name: 1,4-Dimethyl-7-isopropenylazulene
• Synonyms: 1,4-Dimethyl-7-(1-methylvinyl)azulene;1,4-Dimethyl-7-isopropenylazulene;Lactarazulene
• CAS NO: 489-85-0
• Molecular Formula: C15H16
• Molecular Weight: 196.2875
• Mol File: 489-85-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 320.4°Cat760mmHg
• Flash Point: 153.8°C
• Appearance: /
• Density: 0.972g/cm³
• Vapor Pressure: 0.000597mmHg at 25°C
• Refractive Index: 1.587
• CAS DataBase Reference: 1,4-Dimethyl-7-isopropenylazulene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Dimethyl-7-isopropenylazulene(489-85-0)
• EPA Substance Registry System: 1,4-Dimethyl-7-isopropenylazulene(489-85-0)

Safety Data

• Hazardous Substances Data: 489-85-0(Hazardous Substances Data)

Usage

Appearance

Dark blue crystalline hydrocarbon

Source

Derived from chamomile oil

Cosmetics

For its anti-inflammatory and skin-soothing properties

Medical Ointments

For its anti-inflammatory and skin-soothing properties

Dye/Colorant

Due to its intense blue color

Pharmaceutical Potential

Studied for treatment of various skin conditions and inflammatory disorders

Antioxidant Properties

Known for its strong antioxidant properties

Ongoing Research

Use continues to be explored in therapeutic and cosmetic applications

InChI:InChI=1/C15H16/c1-10(2)13-7-5-11(3)14-8-6-12(4)15(14)9-13/h5-9H,1H2,2-4H3

Upstream product

• 67-56-1 methanol 
• 489-84-9 7-isopropyl-1,4-dimethyl-azulene 
• 90052-62-3 7-(2-bromo-1-methylethyl)-1,4-dimethylazulene 
• 128-08-5 N-Bromosuccinimide 

Relevant articles and documents

UNUSUAL REACTIONS OF GUAIAZULENE WITH N-BROMOSUCCINIMIDE AND SYNTHESIS OF VARIOUSLY FUNCTIONALIZED AZULENES USING THESE REACTIONS

Treatment of guaiazulene (Ia) with NBS in benzene gives various, side-chain-brominated compounds, but in hexane it affords exclusively 3-bromoguaiazulene (Id).Compound Id is stable in hexane at 5 deg C in the absence of oxygen, whereas in benzene it changes very rapidly to a mixture of similar compounds as those directly obtained from Ia and NBS in benzene.Possible pathways for the formation of these compounds are briefly discussed.By utilizing these reactions, various kinds of side-chain functionalized azulenes that are otherwise not available by conventional methods can be readily prepared from Ia.

Autooxidation of Solid Guaiazulene and of the Solution in DMF in the Presence of Base or Acid: A Comparative Study of the Product Distribution

Autooxidation of Guaiazulene was examined in detail under the following conditions: in a highly diluted DMF solution, in DMF in the presence of acid or base (at 80-100 deg C), and as solid state under sunlight or in the dark (at 25-50 deg C).In all cases a wide variety of products were obtained (33 separable compounds altogether), and a comparable study on the distribution of the products under the various reaction conditions was made to establish more precise reaction pathways for the formation of these interesting compounds.