489-86-1

Basic information

• Product Name: (-)-GUAIOL
• Synonyms: 5-Azulenemethanol, 1,2,3,4,5,6,7,8-octahydro-alpha,alpha,3,8-tetramethyl-, [3S-(3alpha,5alpha,8alpha)]-;Champaca camphor;Champacol;Guai-1(5)-en-11-ol;Guaiac alcohol;Gualol;L-rel-Guai-1(5)-en-11-ol;2-((3S,8S)-1,2,3,4,5,6,7,8-octahydro-3,8-dimethylazulen-5-yl)propan-2-ol
• CAS NO: 489-86-1
• Molecular Formula: C₁₅H₂₆O
• Molecular Weight: 222.37
• EINECS: 207-702-8
• Mol File: 489-86-1.mol
• Article Data: 1

Chemical Properties

• Melting Point: 91-93 °C(lit.)
• Boiling Point: 132-136℃
• Flash Point: 113.6°C
• Appearance: /
• Density: 0.9714 g/cm3 (20℃)
• Vapor Pressure: 0.000268mmHg at 25°C
• Refractive Index: 1.5100 (589.3 nm 20℃)
• Storage Temp.: 2-8°C
• Solubility: Chloroform (Slightly), Dichloromethane (Sparingly), Ethanol (Slightly), Methanol
• PKA: 15.11±0.29(Predicted)
• Merck: 13,4572
• BRN: 2047993
• CAS DataBase Reference: (-)-GUAIOL(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-GUAIOL(489-86-1)
• EPA Substance Registry System: (-)-GUAIOL(489-86-1)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 489-86-1(Hazardous Substances Data)

Usage

Description

(-)-Guaiol, a bicyclic sesquiterpene alcohol, is a crystalline solid that is insoluble in water but soluble in alcohol. It is characterized by its guaiane skeleton and is naturally found in essential oils extracted from Salvia lanigera and Helitta ongifoliata plants. Additionally, it is a component of guaiac wood oil and is also present in cannabis. (-)-Guaiol exhibits antibacterial activity, making it a potential candidate for various applications.

Uses

Used in Pharmaceutical Industry:
(-)-Guaiol is used as an active pharmaceutical ingredient for its antibacterial properties, which can be utilized in the development of new drugs to combat bacterial infections.
Used in Cosmetics Industry:
(-)-Guaiol can be used as a natural ingredient in the cosmetics industry, where its antibacterial activity can contribute to the development of products with antimicrobial properties, such as skincare and hair care products.
Used in Aromatherapy:
Due to its presence in essential oils, (-)-Guaiol can be used in aromatherapy for its potential therapeutic effects, including relaxation and stress relief.
Used in Flavor and Fragrance Industry:
(-)-Guaiol's natural occurrence in essential oils makes it a suitable candidate for use in the flavor and fragrance industry, where it can be employed to create unique and complex scents for various products.
Used in Research and Development:
(-)-Guaiol's unique chemical properties and natural occurrence in various plants make it an interesting subject for research and development in the fields of chemistry, biology, and pharmacology. It can be studied for potential new applications and synergistic effects with other compounds.

InChI:InChI=1/C15H26O/c1-10-5-7-12(15(3,4)16)9-14-11(2)6-8-13(10)14/h10-12,16H,5-9H2,1-4H3/t10-,11-,12+/m0/s1

Downstream Products

• 3691-12-1 (1S,4S,7R)-7-Isopropenyl-1,4-dimethyl-1,2,3,4,5,6,7,8-octahydro-azulene 
• 88-84-6 1,2,3,4,5,6,7,8-octahydro-1,4-dimethyl-7-(1-methylethylidene)azulene 
• 134-28-1 2-[(3S,5R,8S)-3,8-dimethyl-1,2,3,4,5,6,7,8-octahydroazulen-5-yl]-propan-2-yl acetate 
• 13837-19-9 (3aS)-7-oxo-1t.4t-dimethyl-6-(benzylidene-(ξ))-(3arH.8acH)-decahydro-azulene 
• 489-80-5 guanine 
• 41654-22-2 (-)-α-Isopropyl-γ-acetobuttersaeure-methylester 
• 18374-76-0 (3S,5R,8S)-3,8-dimethyl-5-prop-1-en-2-yl-3,4,5,6,7,8-hexahydro-2H-azulen-1-one 
• 13902-07-3 eudesm-4-en-11-ol 
• 489-84-9 7-isopropyl-1,4-dimethyl-azulene 
• 489-77-0 6-isopropyl-1,4-dimethyl-naphthalene 
• 13744-53-1 2-[(3S,5R,8S)-3,8-dimethyl-1,2,3,4,5,6,7,8-octahydroazulen-5-yl]-propan-2-yl benzoate 
• 3526-75-8 (3aS)-1t.4t-dimethyl-7t-(α-hydroxy-isopropyl)-(3arH.8acH)-decahydro-azulene