489446-42-6 Usage
Description
4-((N-BOC-AMINO)METHYL)PHENYLBORONIC ACID, also known as 4-(Boc-aminomethyl)benzeneboronic acid, is a chemical compound characterized by the presence of a boronic acid functional group and a protected amino group. This molecule is known for its ability to form reversible covalent bonds with diols, making it a versatile building block in various applications.
Uses
Used in Biomimetic Membranes:
4-((N-BOC-AMINO)METHYL)PHENYLBORONIC ACID is used as a key component in the preparation of lipid pore-filled silica thin-film membranes. These membranes are designed for the biomimetic recovery of diluted carbohydrates, leveraging the selective binding properties of the boronic acid group to target specific carbohydrate molecules.
Used in Proteomics Research:
In the field of proteomics, 4-((N-BOC-AMINO)METHYL)PHENYLBORONIC ACID serves as a valuable reagent for the study of proteins and their interactions. 4-((N-BOC-AMINO)METHYL)PHENYLBORONIC ACID's boronic acid functionality allows for the selective capture and analysis of glycoproteins, which are proteins with attached carbohydrate moieties. This selective binding is crucial for the identification and characterization of glycoproteins in complex biological samples.
Check Digit Verification of cas no
The CAS Registry Mumber 489446-42-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,8,9,4,4 and 6 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 489446-42:
(8*4)+(7*8)+(6*9)+(5*4)+(4*4)+(3*6)+(2*4)+(1*2)=206
206 % 10 = 6
So 489446-42-6 is a valid CAS Registry Number.
InChI:InChI=1/C12H18BNO4/c1-12(2,3)18-11(15)14-8-9-4-6-10(7-5-9)13(16)17/h4-7,16-17H,8H2,1-3H3,(H,14,15)
489446-42-6Relevant articles and documents
Design, synthesis and biological evaluation of PSMA/hepsin-targeted heterobivalent ligands
Subedi, Milan,Minn, Il,Chen, Jianbo,Kim, YunHye,Ok, Kiwon,Jung, Yong Woo,Pomper, Martin G.,Byun, Youngjoo
, p. 208 - 218 (2016)
Cell surface biomarkers such as prostate-specific membrane antigen (PSMA) and hepsin have received considerable attention as targets for imaging prostate cancer (PCa) due to their high cell surface expression in such tumors and easy access for imaging pro
QUINOXALINE COMPOUNDS AND USES THEREOF
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Paragraph 00273, (2015/11/09)
This invention provides compounds of formula I and subsets thereof: wherein T, J, R, R4, Rq, o, RA, and RB and subsets thereof are as described in the specification. The compounds are inhibitors of NAMPT and are thus useful for treating cancer, inflammatory conditions, or T-cell mediated autoimmune disease.
Small molecule thienopyrimidine-based protein tyrosine kinase inhibitors
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Page/Page column 40, (2010/02/15)
Various thienopyrimidine-based analog compounds are able to selectively inhibit the Src family of tyrosine kinases. These compounds are useful in the treatment of various diseases including hyperproliferative diseases, hematologic diseases, osteoporosis, neurological diseases, autoimmune diseases, allergic/immunological diseases, or viral infections.