489446-85-7

Basic information

• Product Name: (1R,3R)-N-BOC-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID, 98% E.E.
• Synonyms: (1R,3R)-N-BOC-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID, 98% E.E.;(1R,3R)-N-Boc-1-aminocyclopentane-3-carboxylic acid, 95%, ee:98%;(1R,3R)-N-BOC-1-Aminocyclopentane-3-carboxylic acid,95%,98% ee;3-((tert-butoxycarbonyl)amino)cyclopentanecarboxylic acid;(1R,3R)-N-tert-Butoxycarbonyl-1-aminocyclopentane-3-carboxylic acid;(1R,3R)-N-BOC-1-AMinocyclopentane-3-carboxylic acid, 98% ee, 95% 1GR;(1R,3R)-3-((tert-Butoxycarbonyl)aMino)cyclopentanecarboxylic acid;(1R,3R)-3-[(tert-Butoxycarbonyl)amino]cyclopentane-1-carboxylic acid, tert-Butyl [(1R,3R)-3-carboxycyclopent-1-yl]carbamate
• CAS NO: 489446-85-7
• Molecular Formula: C₁₁H₁₉NO₄
• Molecular Weight: 229.27286
• Mol File: 489446-85-7.mol
• Article Data: 2

Chemical Properties

• Melting Point: 117.3°C
• Boiling Point: 382.5±31.0 °C(Predicted)
• Appearance: White to light yellow/Powder
• Density: 1.15±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 4.62±0.40(Predicted)
• CAS DataBase Reference: (1R,3R)-N-BOC-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID, 98% E.E.(CAS DataBase Reference)
• NIST Chemistry Reference: (1R,3R)-N-BOC-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID, 98% E.E.(489446-85-7)
• EPA Substance Registry System: (1R,3R)-N-BOC-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID, 98% E.E.(489446-85-7)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 489446-85-7(Hazardous Substances Data)

Usage

Description

(1R,3R)-N-BOC-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID, 98% E.E. is a synthetic intermediate with a chemical composition characterized by its chiral centers at the 1R and 3R positions. It is a white to light yellow powder and is predominantly used in the pharmaceutical industry for the synthesis of various compounds.

Uses

Used in Pharmaceutical Synthesis:
(1R,3R)-N-BOC-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID, 98% E.E. is used as a synthetic intermediate for the development of pharmaceutical compounds. Its chiral structure and reactivity make it a valuable building block in the creation of new drugs.
Used in DNA Binding Compounds:
In the field of molecular biology, (1R,3R)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]cyclopentanecarboxylic Acid is used in the preparation of saturated heterocyclic distamycin analogs. These analogs possess DNA binding properties, which can be crucial in the study and manipulation of genetic material for various applications, including gene regulation and the development of targeted therapies.
Different applications in different industries may include:
Used in the Chemical Industry:
(1R,3R)-N-BOC-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID, 98% E.E. is used as a key component in the synthesis of specialty chemicals, leveraging its unique structural features for the development of novel products with specific applications.
Used in the Research and Development Sector:
(1R,3R)-N-BOC-1-AMINOCYCLOPENTANE-3-CARBOXYLIC ACID, 98% E.E. is also utilized in academic and industrial research labs for the exploration of new chemical reactions and the development of innovative methodologies in organic chemistry and drug discovery.

Upstream product

• 693245-53-3 tert-butyl (1R,4S)-3-oxo-2-azabicyclo[2.2.1]heptane-2-carboxylate 
• 200002-41-1 (-)-[(1R,4S)-tert-butyl 3-oxo-2-azabicyclo(2.2.1)hept-5-ene-2-carboxylate] 
• 24424-99-5 di-tert-butyl dicarbonate 
• 130931-83-8 (1S,4R)-2-azabicyclo[2,2,1]hept-5-en-3-one 
• 489446-72-2 (1R,3R)-3-tert-butoxycarbonylaminocyclopentanecarboxylic acid methyl ester 

Downstream Products

• 71869-43-7 (-)-trans-(1R,3R)-3-aminocyclopentane-1-carboxylic acid 
• 1203306-05-1 (1R,3R)-3-aminocyclopentane-1-carboxylic acid hydrochloride 
• 1310731-06-6 tert-butyl (1R,3R)-3-(2-(5-tosyl-5H-pyrrolo[2,3-b]pyrazin-2-yl)hydrazinecarbonyl)cyclopentylcarbamate 
• 489446-72-2 (1R,3R)-3-tert-butoxycarbonylaminocyclopentanecarboxylic acid methyl ester 
• 1315495-82-9 C₂₃H₂₉N₅O₄S 
• 1315495-81-8 C₂₃H₂₇N₅O₆S 
• 1426426-27-8 (1R,3R)-3-amino-cyclopentanecarbonitrile trifluoroacetate 
• 1009075-44-8 ((1R,3R)-3-amino-cyclopentyl)-carbamic acid tert-butyl ester 
• 220497-66-5 (1R,3R)-3-(9-fluorenylmethoxycarbonylamino)cyclopentanecarboxylic acid 

Relevant articles and documents

PYRAZOLO-PYRIMIDIN-AMINO-CYCLOALKYL COMPOUNDS AND THEIR THERAPEUTIC USES

Disclosed herein are pyrazolo-pyrimid in-ami no-cycloalkyl compounds, analogs thereof, pharmaceutical compositions comprising thereof and therapeutic uses therefor.