4896-77-9 Usage
Description
GLYCINE-D5, also known as Deuterated Glycine (G615990), is a non-essential amino acid that plays a crucial role in human development. It is an inhibitory neurotransmitter in the spinal cord and serves as an allosteric regulator of NMDA receptors. GLYCINE-D5 is characterized by its white powder chemical properties.
Uses
Used in Pharmaceutical Industry:
GLYCINE-D5 is used as a non-essential amino acid for human development, contributing to the overall growth and maintenance of the human body.
Used in Neuroscience Research:
GLYCINE-D5 is used as an inhibitory neurotransmitter in the spinal cord, playing a vital role in the regulation of neuronal activity and communication.
Used in Neuroreceptor Regulation:
GLYCINE-D5 is used as an allosteric regulator of NMDA receptors, which are essential for various cognitive functions and synaptic plasticity.
Used in Chemical Synthesis:
GLYCINE-D5, due to its deuterated nature, is used in chemical synthesis processes where the presence of deuterium isotopes can provide unique insights into reaction mechanisms and improve the understanding of molecular interactions.
Check Digit Verification of cas no
The CAS Registry Mumber 4896-77-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,8,9 and 6 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 4896-77:
(6*4)+(5*8)+(4*9)+(3*6)+(2*7)+(1*7)=139
139 % 10 = 9
So 4896-77-9 is a valid CAS Registry Number.
InChI:InChI=1/C2H6N2O/c3-1-2(4)5/h1,3H2,(H2,4,5)/i1D2/hD4
4896-77-9Relevant articles and documents
Ghazanfar et al.
, p. 3439,3440,3442 (1964)
Deuteron Chemical Shift and EFG Tensors in α-Glycine
Mueller, Carmen,Schajor, W.,Zimmermann, H.,Haeberlen, U.
, p. 235 - 246 (2007/10/02)
By computer fitting of resonance lines in deuteron spectra of perdeuterated crystals, deuteron chemical shifts in crystals are measured with an accuracy of +/- 0.3 ppm.Second-order quadrupole shifts must be taken into account.An important advantage of the method is that the measured chemical shifts and the shift tensors are automatically related to EFG tensors which can be assigned easily.The method is applied to α-glycine for which a shift anisotropy Δ? = 21 +/- 9 ppm has been reported for the methylene protons.Full EFG and chemical-shift tensors are reported at both methylene deuteron sites, and motionally averaged tensors are reported for the ND3+ sites.The shift anisotropies Δ? for the methylene deuterons are 4.7 and 9.4 ppm, respectively.Significant differences of the isotropic shifts and quadrupole coupling constants are also observed for these two deuterons.They are interpreted as evidence for the formation of a weak C-H...O hydrogen bond in α-glycine.