490-49-3

Basic information

• Product Name: (-)-FISETINIDOL
• Synonyms: (-)-FISETINIDOL;(2R)-2α-(3,4-Dihydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-3β,7-diol;3,4-Dihydro-2α-(3,4-dihydroxyphenyl)-2H-1-benzopyran-3β,7-diol
• CAS NO: 490-49-3
• Molecular Formula: C₁₅H₁₄O₅
• Molecular Weight: 274.27
• Mol File: 490-49-3.mol
• Article Data: 2

Chemical Properties

• Melting Point: 205-206 °C(Solv: ethyl acetate (141-78-6); ligroine (8032-32-4))
• Boiling Point: 568.2 °C at 760 mmHg
• Flash Point: 297.4 °C
• Appearance: /
• Density: 1.492 g/cm³
• Vapor Pressure: 9.49E-14mmHg at 25°C
• Refractive Index: 1.708
• PKA: 9.56±0.10(Predicted)
• CAS DataBase Reference: (-)-FISETINIDOL(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-FISETINIDOL(490-49-3)
• EPA Substance Registry System: (-)-FISETINIDOL(490-49-3)

Safety Data

• Hazardous Substances Data: 490-49-3(Hazardous Substances Data)

Usage

Description

(-)-Fisetinidol, also known as a tetrahydroxyflavan, is a flavonoid compound with hydroxy groups at positions 3, 7, 3', and 4' on a (2S)-flavan backbone. It is derived from natural sources and has been studied for its potential biological activities and applications.

Uses

Used in Pharmaceutical Industry:
(-)-Fisetinidol is used as a pharmaceutical compound for its potential therapeutic effects. It has been investigated for its antioxidant, anti-inflammatory, and neuroprotective properties, which may contribute to the treatment of various diseases, including neurodegenerative disorders and cardiovascular diseases.
Used in Cosmetic Industry:
In the cosmetic industry, (-)-fisetinidol is used as an active ingredient for its antioxidant and anti-aging properties. It may help protect the skin from environmental stressors, reduce the appearance of fine lines and wrinkles, and promote a more youthful and radiant complexion.
Used in Nutraceutical Industry:
(-)-Fisetinidol is used as a nutraceutical ingredient for its potential health benefits. It can be incorporated into dietary supplements and functional foods to support overall health and well-being, particularly in the areas of cognitive function, immune support, and cardiovascular health.
Used in Research and Development:
(-)-Fisetinidol is also used in research and development for its potential applications in various fields, including drug discovery, functional food development, and cosmetic formulation. Its unique chemical structure and biological activities make it an interesting candidate for further investigation and potential commercialization.

InChI:InChI=1/C15H14O5/c16-10-3-1-8-5-13(19)15(20-14(8)7-10)9-2-4-11(17)12(18)6-9/h1-4,6-7,13,15-19H,5H2/t13-,15+/m0/s1

Upstream product

• 967-27-1 (+)-mollisacacidin 
• 490-32-4 (+/-)-2r-(3,4-Dihydroxy-phenyl)-chroman-3t,4c,7-triol 
• 56961-48-9 2-chloro-3′,4′-dihydroxyacetophenone 
• 42529-03-3 2,3’,4’-triacetoxyacetophenone 
• 863-02-5 (+/-)-3c,7-Diacetoxy-2r-(3,4-diacetoxy-phenyl)-chroman 
• 251909-35-0 2,3',4,4'-tetra-O-methoxymethyl-retro-chalcone 
• 251909-40-7 1-(3',4'-di-O-methoxymethylphenyl)-3-(2'',4''-di-O-methoxymethylphenyl)-1-propanol 
• 251909-45-2 (E)-1-(3',4'-di-O-methoxymethylphenyl)-3-(2'',4''-di-O-methoxymethylphenyl)-propene 
• 13709-06-3 2,4-bis(methoxymethoxy)benzaldehyde 
• 251909-50-9 (1S,2S)-syn-1-(3',4'-di-O-methoxymethylphenyl)-3-(2'',4''-di-O-methoxymethylphenyl)-propane-1,2-diol 
• 127612-93-5 6-Bromo-(-)-fisetinidol 
• 2948-76-7 fisetinidin chloride 

Downstream Products

• 62861-00-1 Tri-O-methyl-(-)-fisetinidol 
• 62849-10-9 (S)-3-(2,4-Dimethoxy-phenyl)-1-(3,4-dimethoxy-phenyl)-1-methoxy-propan-2-ol 
• 95541-47-2 (3R,4R)-3,4-trans-4-<(2R,3S)-2,3-trans-3-acetoxy-3',4',7-trimethoxyflavan-6-yl>-2',4',7-trimethoxyisoflavan 
• 78139-50-1 (2R,3S,4R)-3-acetoxy-4-<(2R,3S)-3-acetoxy-3',4',7-trimethoxyflavan-6-yl>-3',4',7-trimethoxyflavan 
• 78139-50-1 (2R,3S,4S)-3-acetoxy-4-<(2R,3S)-3-acetoxy-3',4',7-trimethoxyflavan-6-yl>-3',4',7-trimethoxyflavan 
• 78139-49-8 (2R,3S,4R)-2,3-trans-3,4-trans-3,3',4',7-tetramethoxy-4-<(2R,3S)-2,3-trans-3-acetoxy-3',4',7-trimethoxyflavan-6-yl>flavan 
• 137299-03-7 3',4'-di-O-methyl-(-)-fisetinidol 
• 127612-93-5 6-Bromo-(-)-fisetinidol 
• 117479-75-1 tri-O-methyl-3-O-acetyl-(-)-fisetinidol-(4β,6)-tetra-O-methyl-3-O-acetyl-(-)-robinetinidol 
• 127644-59-1 (+)-mopanane-(4β,6)-(-)-fisetinidol 
• 127644-60-4 (+)-mopanane-(4β,6)-(+)-epifisetinidol 
• 127612-83-3 1-<(2R,3S)-2,3-trans-3,3',4',7-tetrahydroxyflavan-6-yl>-3-(2,4-dihydroxyphenyl)-1-(3,4-dihydroxyphenyl)-propan-2-ol 
• 127644-69-3 1-<(2S,3S)-2,3-cis-3,3',4',7-tetrahydroxyflavan-6-yl>-3-(2,4-dihydroxyphenyl)-1-(3,4-dihydroxyphenyl)-propan-2-ol 
• 118964-34-4 (-)-Fisetinidol-(4α,8)-(+)-catechin 4-O(E)-methyl ether 

Relevant articles and documents

Stereoselective Synthesis of Flavonoids. Part 8. Free Phenolic Flavan-3-ol Diastereomers

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