491601-38-8

Basic information

• Product Name: 2-PHENYL-5-(TRIFLUOROMETHYL)-1H-INDOLE
• Synonyms: 1H-INDOLE, 2-PHENYL-5-(TRIFLUOROMETHYL)-;2-PHENYL-5-(TRIFLUOROMETHYL)-1H-INDOLE
• CAS NO: 491601-38-8
• Molecular Formula: C15H10F3N
• Molecular Weight: 261.245
• Mol File: 491601-38-8.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• Density: 1.301
• CAS DataBase Reference: 2-PHENYL-5-(TRIFLUOROMETHYL)-1H-INDOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-PHENYL-5-(TRIFLUOROMETHYL)-1H-INDOLE(491601-38-8)
• EPA Substance Registry System: 2-PHENYL-5-(TRIFLUOROMETHYL)-1H-INDOLE(491601-38-8)

Safety Data

• Hazardous Substances Data: 491601-38-8(Hazardous Substances Data)

Upstream product

• 1054566-84-5 C₁₅H₁₀F₃N₃ 
• 1033002-26-4 2-(2-phenylethynyl)-4-trifluoromethylphenylamine 
• 163444-17-5 2-iodo-4-(trifluoromethyl)aniline 
• 440363-04-2 2-(2-trimethylsilylethynyl)-4-trifluoromethylaniline 
• 878133-02-9 2-ethynyl-4-(trifluoromethyl)aniline 
• 536-74-3 phenylacetylene 
• 100-42-5 styrene 
• 132839-58-8 2-bromo-1-nitro- 4-(trifluoromethyl)benzene 
• 6783-05-7 trans-2-phenylvinylboronic acid 
• 455-14-1 4-trifluoromethylphenylamine 
• 70-11-1 α-bromoacetophenone 
• 1449516-94-2 C₁₆H₁₀BrF₃N₂ 
• 1181455-10-6 C₁₅H₁₂F₃N₃ 
• 1181455-43-5 C₁₅H₁₀F₃N₃ 

Downstream Products

• 1476035-15-0 1-phenyl-2-(2-phenyl-5-(trifluoromethyl)-1H-indol-3-yl)ethane-1,2-dione 
• 1417819-59-0 2-phenyl-6-(trifluoromethyl)-4H-benzo[d][1,3]oxazin-4-one 
• 1613132-75-4 C₁₇H₁₁ClF₃NO 
• 1613133-17-7 1-(5-amino-3-thioxo-2,3,4,5-tetrahydro-1,2,4-triazin-6-yl)-2-phenyl-5-(trifluoromethyl)-1H-indole-3-carboxamide 
• 1613133-11-1 1-(5-amino-3-thioxo-2,3,4,5-tetrahydro-1,2,4-triazin-6-yl)-2-phenyl-5-(trifluoromethyl)-1H-indole-3-carboxylic acid 
• 1613132-99-2 1-(1-(5-amino-3-thioxo-2,3,4,5-tetrahydro-1,2,4-triazin-6-yl)-2-phenyl-5-(trifluoromethyl)-1H-indol-3-yl)ethanone 
• 1613132-93-6 6-(3-allyl-2-phenyl-5-(trifluoromethyl)-1H-indol-1-yl)-5-amino-4,5-dihydro-1,2,4-triazine-3(2H)-thione 
• 1613132-87-8 C₁₈H₁₄F₃N₅S 
• 1613132-81-2 C₁₈H₁₃F₃N₄S 

Relevant articles and documents

Copper-Catalyzed Enantioselective C-H Arylation between 2-Arylindoles and Hypervalent Iodine Reagents

The copper-catalyzed enantioselective C-H arylation between 2-arylindoles and hypervalent iodine reagents has been successfully developed, which provides a convenient and economical route to the highly atroposelective synthesis of axially chiral indole de

Pd-Catalyzed Reductive Cyclization of Nitroarenes with CO2 as the CO Source

A reductive amination process that constructs indoles, carbazoles or benzimidazoles from nitroarenes – irrespective of their electronic or steric nature – was developed that uses CO2 as the source of CO. The process is robust, tolerating common gaseous components of flue gas (H2S, SO2, NO and H2O) without adversely affecting the reductive cyclization.

Palladium-Catalyzed Formation of N-Heteroarenes from Nitroarenes using Molybdenum Hexacarbonyl as the Source of Carbon Monoxide

The development of a method that employs a two-chamber reaction vessel and uses molybdenum hexacarbonyl [Mo(CO)6] as the carbon monoxide (CO) source for the palladium-catalyzed transformation of nitroarenes into indoles or imidazoles is reported.