4919-37-3 Usage
Description
4-Hydroxy-3,5-dimethylbenzoic acid is an organic compound characterized by its off-white to light pink or light beige crystalline appearance. It is a derivative of benzoic acid with a hydroxyl group at the 4th position and two methyl groups at the 3rd and 5th positions. This chemical structure endows it with unique properties that make it suitable for various applications across different industries.
Uses
Used in Pharmaceutical Industry:
4-Hydroxy-3,5-dimethylbenzoic acid is used as a reagent for potent TTR amyloidogenesis inhibitors. It plays a crucial role in the development of therapeutic agents that target transthyretin (TTR) amyloidosis, a condition characterized by the abnormal accumulation of TTR protein in tissues, leading to various diseases.
Used in Agrochemical Industry:
In the agrochemical sector, 4-Hydroxy-3,5-dimethylbenzoic acid serves as an important intermediate in the synthesis of various compounds. Its presence in this industry is vital for the development of new and improved agrochemical products, such as pesticides and herbicides, which are essential for maintaining agricultural productivity and crop protection.
Used in Dye Industry:
4-Hydroxy-3,5-dimethylbenzoic acid is also utilized in the dye industry as an intermediate for the production of various dyestuffs. Its unique chemical properties contribute to the development of new and innovative dyes with enhanced color properties and improved performance characteristics.
Used in Chemical Synthesis:
4-Hydroxy-3,5-dimethylbenzoic acid is used in the preparation of mexiletine derivatives. Mexiletine is an antiarrhythmic drug used to treat abnormal heart rhythms. The synthesis of mexiletine derivatives involves the use of 4-Hydroxy-3,5-dimethylbenzoic acid as a key intermediate, highlighting its importance in the pharmaceutical sector.
Check Digit Verification of cas no
The CAS Registry Mumber 4919-37-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,9,1 and 9 respectively; the second part has 2 digits, 3 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 4919-37:
(6*4)+(5*9)+(4*1)+(3*9)+(2*3)+(1*7)=113
113 % 10 = 3
So 4919-37-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H10O3/c1-5-3-7(9(11)12)4-6(2)8(5)10/h3-4,10H,1-2H3,(H,11,12)/p-1
4919-37-3Relevant articles and documents
New secondary metabolites from Allium victorialis
Khan, Sadia,Fatima, Itrat,Hussain Kazmi, Mehdi,Malik, Abdul
, p. 1176 - 1181 (2013)
Allumines A and B (1 and 2, resp.), two new steroidal alkaloids, and a new cyclopentene derivative, 3, were isolated from the CHCl3-soluble fraction of the whole plant of Allium victorialis. Their structures were elucidated by spectroscopic techniques, including 1D- and 2D-NMR spectroscopy. Copyright
Preparation method of propofol and structural analogues of propofol
-
Paragraph 0074-0080, (2017/08/28)
The invention relates to a preparation method of propofol and structural analogues of propofol. The preparation method comprises the steps as follows: preparing an intermediate from p-hydroxybenzoic acid and alkyl alcohol as raw materials under the action of a solid acid catalyst, and then preparing a target product by a decarboxylase reaction. The preparation method has the characteristics of being green in synthesis, realizing biotransformation, causing little pollution, producing few by-products and the like, and is suitable for industrial production; the purity of the prepared products such as propofol is 99.6% or higher, which meets various medicinal standards.
Facile cleavage of ethers in ionic liquid
Cheng, Lili,Aw, Carlin,Ong, Siew Siang,Lu, Yixin
supporting information; experimental part, p. 2008 - 2010 (2009/08/14)
Various alkyl ethers were efficiently cleaved by treating them with pyridinium halides in ionic liquid, and the desired products were obtained in excellent yields.
