4926-26-5 Usage
Description
2-BROMO-4,6-DIMETHYLPYRIDINE is an organic compound characterized by its light yellow crystalline structure. It is a derivative of pyridine, a heterocyclic compound, with two methyl groups at the 4 and 6 positions and a bromine atom at the 2 position. 2-BROMO-4,6-DIMETHYLPYRIDINE is known for its unique chemical properties and reactivity, making it a valuable component in various chemical reactions and syntheses.
Uses
Used in Pharmaceutical Industry:
2-BROMO-4,6-DIMETHYLPYRIDINE is used as a reactant in the regioselective and diastereoselective syntheses of the natural product CCR5 antagonist anibamine and its three olefin isomers. This application is significant because anibamine is a potential therapeutic agent for various diseases, including HIV and other conditions that involve the CCR5 receptor.
Used in Chemical Synthesis:
Due to its unique structure and reactivity, 2-BROMO-4,6-DIMETHYLPYRIDINE can be employed as a building block or intermediate in the synthesis of various organic compounds. Its ability to participate in regioselective and diastereoselective reactions makes it a valuable asset in the development of new molecules with specific properties and applications.
Used in Research and Development:
2-BROMO-4,6-DIMETHYLPYRIDINE can be utilized in research and development settings to explore its potential applications and properties further. Its unique structure and reactivity make it an interesting candidate for studying various chemical reactions and mechanisms, which could lead to the discovery of new compounds and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 4926-26-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,9,2 and 6 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 4926-26:
(6*4)+(5*9)+(4*2)+(3*6)+(2*2)+(1*6)=105
105 % 10 = 5
So 4926-26-5 is a valid CAS Registry Number.
4926-26-5Relevant articles and documents
QUINOLINE DERIVATIVES AS SMO INHIBITORS
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Paragraph 0512; 0513, (2017/02/28)
Disclosed are quinoline derivatives as hedgehog pathway inhibitors, especially as SMO inhibitors. Compounds of the present invention can be used in treating diseases relating to hedgehog pathway including cancer.
Regio- and stereoselective syntheses of the natural product CCR5 antagonist anibamine and its three olefin isomers
Zhang, Feng,Zaidi, Saheem,Haney, Kendra M.,Kellogg, Glen E.,Zhang, Yan
experimental part, p. 7945 - 7952 (2011/11/30)
The syntheses of the natural product anibamine and its three olefin isomers have been achieved concisely and efficiently via highly regio- and stereoselective reactions. The crucial steps included a regioselective palladium-catalyzed alkynylation by Sonogashira coupling and a stereoselective Suzuki coupling. Further conformation analyses and in vitro calcium mobilization studies were carried out to characterize the compounds' biological properties.
2-(1H-INDAZOL-6-YLAMINO)-BENZAMIDE COMPOUNDS AS PROTEIN KINASES INHIBITORS USEFUL FOR THE TREATMENT OF OPHTALMIC DISEASES
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Page 50, (2010/02/07)
Indazole compounds that modulate and/or inhibit the ophthalmic diseases and the activity of certain protein kinases are described. These compounds and pharmaceutical compositions containing them are capable of mediating tyrosine kinase signal transduction and thereby modulate and/or inhibit unwanted cell proliferation. The invention is also directed to the therapeutic or prophylactic use of pharmaceutical compositions containing such compounds, and to methods of treating ophthalmic diseases and cancer and other disease states associated with unwanted angiogenesis and/or cellular proliferation, such as diabetic retinopathy, neovascular glaucoma,rheumatoid arthritis, and psoriasis, by administering effective amounts of such compounds.
