4931-82-2

Basic information

• Product Name: L-Proline, 5-oxo-1-(2-propenyl)- (9CI)
• Synonyms: L-Proline, 5-oxo-1-(2-propenyl)- (9CI);5-oxo-1-(2-propen-1-yl)-L-Proline
• CAS NO: 4931-82-2
• Molecular Formula: C₈H₁₁NO₃
• Molecular Weight: 169.17784
• Product Categories: PYRROLE
• Mol File: 4931-82-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: L-Proline, 5-oxo-1-(2-propenyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: L-Proline, 5-oxo-1-(2-propenyl)- (9CI)(4931-82-2)
• EPA Substance Registry System: L-Proline, 5-oxo-1-(2-propenyl)- (9CI)(4931-82-2)

Safety Data

• Hazardous Substances Data: 4931-82-2(Hazardous Substances Data)

Upstream product

• 122169-90-8 (S)-1-Allyl-5-oxo-pyrrolidine-2-carboxylic acid allyl ester 
• 98-79-3 L-Pyroglutamic acid 
• 4931-66-2 methyl (S)-pyroglutamate 
• 4931-81-1 (S)-1-Allyl-5-oxo-pyrrolidine-2-carboxylic acid methyl ester 
• 107-05-1 3-chloroprop-1-ene 

Downstream Products

• 122080-59-5 (S)-1-Allyl-5-oxo-pyrrolidine-2-carboselenoic acid Se-phenyl ester 
• 2687-97-0 1-allyl-2-pyrrolidinone 

Relevant articles and documents

Di-μ-hydroxy-bis(N,N,N′,N′-tetramethylenediamine)-copper(II) chloride [Cu(OH)·TMEDA]2Cl2: An efficient, practical catalyst for benzylation and allylation of amides

An efficient protocol for the benzylation or allylation of amides using the corresponding benzyl or allyl chlorides as electrophiles under basic conditions with commercially available 5 mol % of [Cu(OH)TMEDA]2Cl2 as catalyst was developed. Under these conditions, unprotected amino acids were benzylated without any racemization.

CARBONYL RADICAL CYCLIZATIONS: PREPARATION OF SOME HETEROCYCLIC KETONES

It has been possible to synthesize 3-methylchromanone, 3-methylthiochromanone and 2,3-dihydro-3-methylquinolin-4-one from salicylic acid, thiosalicylic acid and anthranilic acid respectively by carbonyl radical cyclizations.