494799-77-8 Usage
Molecular Structure
Contains an indole ring, a carboxylic acid group, a cyclohexyl group, and a furanyl group.
Molecular Weight
287.33 g/mol (calculated from the molecular formula).
Appearance
Not provided in the material, but likely a solid based on the presence of a carboxylic acid group.
Applications
Commonly used in the synthesis of pharmaceuticals and agrochemicals.
Potential Properties
Has potential therapeutic and pesticidal properties.
Possible Uses
Development of new drugs for various medical conditions and protection of crops from pests and diseases.
Research and Industrial Potential
Unique molecular structure makes it a promising candidate for further research and potential industrial use.
Check Digit Verification of cas no
The CAS Registry Mumber 494799-77-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,4,7,9 and 9 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 494799-77:
(8*4)+(7*9)+(6*4)+(5*7)+(4*9)+(3*9)+(2*7)+(1*7)=238
238 % 10 = 8
So 494799-77-8 is a valid CAS Registry Number.
494799-77-8Relevant articles and documents
Improved replicon cellular activity of non-nucleoside allosteric inhibitors of HCV NS5B polymerase: From benzimidazole to indole scaffolds
Beaulieu, Pierre L.,Gillard, James,Bykowski, Darren,Brochu, Christian,Dansereau, Nathalie,Duceppe, Jean-Simon,Hache, Bruno,Jakalian, Araz,Lagace, Lisette,LaPlante, Steven,McKercher, Ginette,Moreau, Elaine,Perreault, Stephane,Stammers, Timothy,Thauvette, Louise,Warrington, Jeff,Kukolj, George
, p. 4987 - 4993 (2007/10/03)
Benzimidazole-based allosteric inhibitors of the hepatitis C virus (HCV) NS5B polymerase were diversified to a variety of topologically related scaffolds. Replacement of the polar benzimidazole core by lipophilic indoles led to inhibitors with improved potency in the cell-based subgenomic HCV replicon system. Transposing the indole scaffold into a previously described series of benzimidazole-tryptophan amides generated the most potent inhibitors of HCV RNA replication in cell culture reported to date in this series (EC50 ～ 50 nM).
