495-80-7 Usage
Description
Tropine isobutyrate is an alkaloid derived from the bark of Brugiera sexangula and B. exaristata. It is formed by the combination of tropine and isobutyric acid, which can be obtained through alkaline or acid hydrolysis. Tropine isobutyrate has unique properties that make it suitable for various applications across different industries.
Uses
Used in Pharmaceutical Industry:
Tropine isobutyrate is used as an active pharmaceutical ingredient for the development of various medications. Its unique chemical structure allows it to interact with specific biological targets, making it a valuable compound in the creation of new drugs.
Used in Chemical Synthesis:
Tropine isobutyrate serves as a key intermediate in the synthesis of other complex organic compounds. Its versatile structure can be further modified to produce a wide range of chemical products, including pharmaceuticals, agrochemicals, and specialty chemicals.
Used in Research and Development:
Due to its unique properties and potential applications, Tropine isobutyrate is used as a research compound in various scientific studies. It helps researchers understand the structure-activity relationships of different molecules and contributes to the development of new drugs and materials.
Used in Analytical Chemistry:
Tropine isobutyrate can be employed as a reference compound or a standard in analytical chemistry. Its well-defined structure and properties make it suitable for calibrating instruments and validating analytical methods, ensuring accurate and reliable results in various chemical analyses.
References
Loder, Russell, Austral. J. Chem., 22, 1271 (1969)
Check Digit Verification of cas no
The CAS Registry Mumber 495-80-7 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,9 and 5 respectively; the second part has 2 digits, 8 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 495-80:
(5*4)+(4*9)+(3*5)+(2*8)+(1*0)=87
87 % 10 = 7
So 495-80-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H21NO2/c1-8(2)12(14)15-11-6-9-4-5-10(7-11)13(9)3/h8-11H,4-7H2,1-3H3/t9-,10+,11?
495-80-7Relevant articles and documents
Insight into the Mechanism of the Acylation of Alcohols with Acid Anhydrides Catalyzed by Phosphoric Acid Derivatives
Hayashi, Hiroyuki,Yasukochi, Shotaro,Sakamoto, Tatsuhiro,Hatano, Manabu,Ishihara, Kazuaki
, p. 5197 - 5212 (2021/04/12)
Insight into the mechanism of a safe, simple, and inexpensive phosphoric acid (H3PO4)-catalyzed acylation of alcohols with acid anhydrides is described. The corresponding in situ-generated diacylated mixed anhydrides, unlike traditionally proposed monoacylated mixed anhydrides, are proposed as the active species. In particular, the diacylated mixed anhydrides act as efficient catalytic acyl transfer reagents rather than as Br?nsted acid catalysts simply activating acid anhydrides. Remarkably, highly efficient phosphoric acid (1-3 mol %)-catalyzed acylation of alcohols with acid anhydrides was achieved and a 23 g scale synthesis of an ester was demonstrated. Also, phosphoric acid catalyst was effective for synthetically useful esterification from carboxylic acids, alcohols, and acid anhydride. Moreover, with regard to recent developments in chiral 1,1′-bi-2-naphthol (BINOL)-derived phosphoric acid diester catalysts toward asymmetric kinetic resolution of alcohols by acylation, some phosphate diesters were examined. As a result, a 31P NMR study and a kinetics study strongly supported not only the acid-base cooperative mechanism as previously proposed by other researchers but also the mixed anhydride mechanism as presently proposed by us.
Esterification of tropine in cultured tissues of duboisia myoporoides
Kitamura, Yoshie,Miura, Hiroshi,Sugii, Michiyasu
, p. 2541 - 2542 (2007/10/02)
Tropine was converted into acetyltropine in callus cultures Duboisia myoporoides, while in shoot cultures butropine was found as an esterified product.
