49572-76-1

Basic information

• Product Name: 2-Propen-1-one, 1-(6-hydroxy-4,7-dimethoxy-5-benzofuranyl)-3-phenyl-
• CAS NO: 49572-76-1
• Molecular Formula: C19H16O5
• Molecular Weight: 324.333
• Mol File: 49572-76-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-one, 1-(6-hydroxy-4,7-dimethoxy-5-benzofuranyl)-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-one, 1-(6-hydroxy-4,7-dimethoxy-5-benzofuranyl)-3-phenyl-(49572-76-1)
• EPA Substance Registry System: 2-Propen-1-one, 1-(6-hydroxy-4,7-dimethoxy-5-benzofuranyl)-3-phenyl-(49572-76-1)

Safety Data

• Hazardous Substances Data: 49572-76-1(Hazardous Substances Data)

Upstream product

• 484-51-5 5-acetyl-6-hydroxy-4,7-dimethoxybenzofuran 
• 100-52-7 benzaldehyde 
• 82-02-0 Khellin 

Downstream Products

• 62061-92-1 1-benzyl-6-(6-hydroxy-4,7-dimethoxy-benzofuran-5-yl)-2-oxo-4-phenyl-1,2,3,4-tetrahydro-pyridine-3-carboxylic acid benzylamide 
• 61340-64-5 5-(2-amino-6-phenyl-6H-[1,3]thiazin-4-yl)-4,7-dimethoxy-benzofuran-6-ol 
• 6430-96-2 5-(1,5-diphenyl-4,5-dihydro-1H-pyrazol-3-yl)-4,7-dimethoxy-benzofuran-6-ol 
• 61340-52-1 4,7-dimethoxy-5-(5-phenyl-4,5-dihydro-isoxazol-3-yl)-benzofuran-6-ol 
• 61340-56-5 4,7-dimethoxy-5-(3-phenyl-4,5-dihydro-isoxazol-5-yl)-benzofuran-6-ol 
• 1355094-17-5 N-(4,9-dimethoxy-5-styryl-7H-furo[3,2-g]chromen-7-ylidene)benzenamine 
• 1355094-19-7 4,9-dimethoxy-5-styryl-7H-furo[3,2-g]chromen-7-one 
• 102078-28-4 3t-phenyl-1-(4,6,7-trimethoxy-benzofuran-5-yl)-propenone 
• 92663-31-5 C₃₁H₂₅O₅P 
• 92663-54-2 Phosphoric acid 4,7-dimethoxy-5-[(E)-(3-phenyl-acryloyl)]-benzofuran-6-yl ester diethyl ester 
• 61340-60-1 (3,4-diphenyl-4,5-dihydro-isoxazol-5-yl)-(6-hydroxy-4,7-dimethoxy-benzofuran-5-yl)-methanone 
• 61340-48-5 (4-phenyl-4,5-dihydro-1H-pyrazol-3-yl)-(4,6,7-trimethoxy-benzofuran-5-yl)-methanone 
• 55008-32-7 2-benzylidene-4,8-dimethoxy-benzo[1,2-b;5,4-b']difuran-3-one 

Relevant articles and documents

FURANOCHALCONES AS INHIBITORS OF CYP1A1, CYP1A2 AND CYP1B1 FOR CANCER CHEMOPREVENTION

The present invention relates to the furanochalcone class of compounds of general formula A. The present invention particularly relates to the synthesis of furanochalcones and their CYP1A1, CYP1A2 and CYP1B1 inhibitory activity. In addition, the invention relates to the prevention or treatment of cancer caused by polyaromatic hydrocarbons (PAHs), 4-nitroquinoline-1-oxide, and N-nitroso-N- methylurea, heterocyclic amines, estrogen and 17β-estradiol, resulting from the inhibition of CYP1A1, CYP1A2 and CYP1B1 enzymes.

Khellinone Derivatives as Blockers of the Voltage-Gated Potassium Channel Kv1.3: Synthesis and Immunosuppressive Activity

The voltage-gated potassium channel Kv1.3 constitutes a promising new target for the treatment of T-cell-mediated autoimmune diseases such as multiple sclerosis. In this study, we report the discovery of two new classes of Kv1.3 blockers based on the natu