496-49-1 Usage
Description
Hygrine is a pyrrolidine alkaloid derivative that possesses antispasmodic activity. It is found in various plant sources, including Datura stramonium and Erythroxylon coca Lam. Hygrine serves as an immediate precursor of Cuscohygrine in Scopolia lurida and Hyoscyamine in Datura stramonium.
Uses
Used in Pharmaceutical Industry:
Hygrine is used as an antispasmodic agent for its ability to relax smooth muscles and alleviate spasms. This property makes it valuable in the development of medications targeting conditions involving muscle spasms or involuntary contractions.
Used in Botanical Research:
As a natural alkaloid derivative, hygrine is utilized in botanical research to study its role in plant defense mechanisms and its potential applications in medicine. Its presence in various plant species also aids in understanding the biosynthetic pathways of alkaloids and their ecological significance.
Used in Toxicological Studies:
Due to its occurrence in plants like Datura stramonium and Erythroxylon coca Lam., hygrine is also used in toxicological studies to investigate its effects on the human body and to develop methods for detection and treatment of poisoning caused by these plants.
Check Digit Verification of cas no
The CAS Registry Mumber 496-49-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,9 and 6 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 496-49:
(5*4)+(4*9)+(3*6)+(2*4)+(1*9)=91
91 % 10 = 1
So 496-49-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H15NO/c1-7(10)6-8-4-3-5-9(8)2/h8H,3-6H2,1-2H3/t8-/m1/s1
496-49-1Relevant articles and documents
A short synthesis of (+)-hygrine
Arévalo-García, Enzo B.,Colmenares, Juan Carlos Q.
, p. 3995 - 3996 (2008/09/20)
The synthesis of the alkaloid hygrine in a series of six steps starting from readily available proline N-methyl derivative (5) is described.
