49619-45-6

Basic information

• Product Name: Benzoic acid, 2-nitro-, anhydride
• CAS NO: 49619-45-6
• Molecular Formula: C14H8N2O7
• Molecular Weight: 316.227
• Mol File: 49619-45-6.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2-nitro-, anhydride(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-nitro-, anhydride(49619-45-6)
• EPA Substance Registry System: Benzoic acid, 2-nitro-, anhydride(49619-45-6)

Safety Data

• Hazardous Substances Data: 49619-45-6(Hazardous Substances Data)

Upstream product

• 610-14-0 2-nitrobenzyl chloride 
• 552-89-6 2-nitro-benzaldehyde 
• 552-16-9 ortho-nitrobenzoic acid 
• 100-51-6 benzyl alcohol 

Downstream Products

• 872267-40-8 7-hydroxy-2-(2-nitro-phenyl)-3-phenyl-chromen-4-one 
• 65671-96-7 2-(2-amino-phenyl)-7-methoxy-3-phenyl-chromen-4-one 
• 65671-94-5 7-methoxy-2-(2-nitro-phenyl)-3-phenyl-chromen-4-one 
• 31042-59-8 phenyl 2-nitrobenzoate 

Relevant articles and documents

Cu-MOF: An efficient heterogeneous catalyst for the synthesis of symmetric anhydrides: Via the C-H bond activation of aldehydes

In this paper, an efficient and straightforward synthetic approach for the preparation of a number of symmetric carboxylic anhydrides was reported using Cu2(BDC)2(DABCO) as an efficient heterogeneous catalyst via the C-H bond activation of aldehydes with excellent yields and simple work up. This C-H bond activation reaction appears simple and convenient, has a wide substrate scope and makes use of cheap, abundant, and easily available reagents. The Cu-MOF catalyst was recycled and reused four times without any loss of catalytic activity.

A mild, clean, and simple synthesis of symmetrical carboxylic anhydrides from carboxylic acides using a polymer supported tosyl chloride

The use of polymeric reagents simplifies routine acylation of carboxylic acid because it eliminates the traditional purification. We describe the use of readily available cross-linked poly(4-vinylpyridine) supported tosyl chloride, [P4VP].TsCl, in the suspended solution phase synthesis of symmetrical anhydrides from carboxylic acids in the presence of K2CO3 in high yields and purity. The products can be obtained by filtration and evaporation of the solvent.

Mild and efficient synthesis of carboxylic acid anhydrides from carboxylic acids and triazine coupling reagents

Anhydrides of carboxylic acids were obtained in 53%-95% yield by treatment of appropriate carboxylic acids with 2-chloro-4,6-dimethoxy-1,3,5-triazine (CDMT) or 2,4-dichloro-6-methoxy-1,3,5-triazine (DCMT) in the presence of N-methylmorpholine. It has been proved that synthesis proceeds via triazine active esters 3a,b, which are able to acylate carboxylate anion but not less nucleophilic carboxylic acid.