4965-26-8

Basic information

• Product Name: 5-Nitrobenzothiophene
• Synonyms: 5-NITROBENZOTHIOPHENE;5-nitrobenzo[b]thiophene;Benzo[b]thiophene, 5-nitro-
• CAS NO: 4965-26-8
• Molecular Formula: C₈H₅NO₂S
• Molecular Weight: 179.2
• Mol File: 4965-26-8.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 324.558°C at 760 mmHg
• Flash Point: 150.088°C
• Appearance: /
• Density: 1.435g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.714
• Storage Temp.: 2-8°C(protect from light)
• CAS DataBase Reference: 5-Nitrobenzothiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Nitrobenzothiophene(4965-26-8)
• EPA Substance Registry System: 5-Nitrobenzothiophene(4965-26-8)

Safety Data

• Hazardous Substances Data: 4965-26-8(Hazardous Substances Data)

Usage

General Description

5-Nitrobenzothiophene is a chemical compound with the molecular formula C8H5NO2S. It is a yellow solid that is soluble in organic solvents and has a melting point of 105-107°C. 5-Nitrobenzothiophene is considered a heterocyclic compound and contains a benzene ring fused to a thiophene ring with a nitro group attached to the 5-position of the thiophene ring. 5-Nitrobenzothiophene is used in the synthesis of pharmaceuticals and agrochemicals due to its potential for biological activity. It is also used as a building block in organic synthesis and as a precursor to other chemical compounds. However, 5-Nitrobenzothiophene is known to be toxic and is harmful if swallowed or inhaled, and it may cause skin and eye irritation upon contact.

InChI:InChI=1/C8H5NO2S/c10-9(11)7-1-2-8-6(5-7)3-4-12-8/h1-5H

Upstream product

• 20532-38-1 5-iodobenzo[b]thiophene 
• 81146-79-4 1-[(2,2-diethoxyethyl)sulfanyl]-4-nitrobenzene 
• 2365-48-2 Methyl thioglycolate 
• 6361-21-3 2-chloro-5-nitrobenzaldehyde 
• 20699-86-9 methyl 5-nitrobenzo[b]thiophene-2-carboxylate 
• 25785-09-5 ethyl 5-nitro-2-benzo[b]thiophenecarboxylate 
• 869624-56-6 (1E,3Z)-3-(4-methanesulfonyl-2-nitrobuta-1,3-dien-1-yl)thiophene 
• 81146-80-7 (4-nitro-phenylsulfanyl)-acetaldehyde dimethylacetal 
• 6345-55-7 5-nitrobenzo[b]thiophene-2-carboxylic acid 

Downstream Products

• 1935534-79-4 3-bromo-2-chlorobenzo[b]thiophen-5-amine 
• 16957-97-4 3-bromobenzothiophene S,S-dioxide 
• 127973-90-4 N-{3-[4-(2-Chloro-benzenesulfonylaminocarbonyl)-2-methoxy-benzyl]-benzo[b]thiophen-5-yl}-2-cyclopentyl-acetamide 
• 127973-89-1 2-Cyclopentyl-N-{3-[2-methoxy-4-(toluene-2-sulfonylaminocarbonyl)-benzyl]-benzo[b]thiophen-5-yl}-acetamide 
• 107786-74-3 N-[4-[5-(cyclopentyloxycarbonyl)aminobenzo[b]thien-3-ylmethyl]-3-methoxybenzoyl]benzenesulphonamide 
• 107786-72-1 methyl 4-<<5-<<(cyclopentyloxy)carbonyl>amino>benzothien-3-yl>methyl>-3-methoxybenzoate 
• 127973-87-9 methyl 4-<<5-(2-cyclopentylacetamido)benzothien-3-yl>methyl>-3-methoxybenzate 
• 107786-73-2 4-<<5-<<(cyclopentyloxy)carbonyl>amino>benzothien-3-yl>methyl>-3-methoxybenzoic acid 
• 127973-88-0 4-<<5-(2-cyclopentylacetamido)benzothien-3-yl>methyl>-3-methoxybenzoic acid 
• 107754-49-4 methyl 4-<(5-aminobenzothien-3-yl)methyl>-3-methoxybenzoate 
• 19301-35-0 benzo[b]thiophen-5-ol 
• 433303-94-7 1-(5-benzo[b]thiophenyl)piperazine 
• 20532-28-9 5-aminobenzo[b]thiophene 
• 107754-50-7 methyl 3-methoxy-4-<(5-nitrobenzothien-3-yl)methyl>benzoate 

Relevant articles and documents

Photoinduced Iron-Catalyzed ipso-Nitration of Aryl Halides via Single-Electron Transfer

A photoinduced iron-catalyzed ipso-nitration of aryl halides with KNO2 has been developed, in which aryl iodides, bromides, and some of aryl chlorides are feasible. The mechanism investigations show that the in situ formed iron complex by FeSO4, KNO2, and 1,10-phenanthroline acts as the light-harvesting photocatalyst with a longer lifetime of the excited state, and the reaction undergoes a photoinduced single-electron transfer (SET) process. This work represents an example for the photoinduced iron-catalyzed Ullmann-type couplings.

HETEROARYL COMPOUNDS AS INHIBITORS OF PROGRAMMED NECROSIS PATHWAY, COMPOSITION AND METHOD USING THE SAME

The present disclosure provides heteroaryl compounds of Formula (I), processes for their preparation, pharmaceutical compositions containing them, and their use in the treatment of diseases and disorders, arising from or related to the programmed necrosis pathway.

Bicyclic heterocyclic anthranilic diamides as ryanodine receptor modulators with insecticidal activity

The diamide insecticides act on the ryanodine receptor (RyR). The synthesis of various bicyclic anthranilic derivatives is reported. Their activity against the insect ryanodine receptor (RyR) and their insecticidal activity in the greenhouse is presented,