496808-05-0 Usage
Derivative of piperazine
Heterocyclic organic compound 2-(piperazin-1-yl)acetic acid is derived from piperazine, which is a heterocyclic organic compound containing a ring of carbon and nitrogen atoms.
Physical appearance
White crystalline powder The compound appears as a white, crystalline solid in powder form.
Solubility
Soluble in water, slightly soluble in ethanol 2-(piperazin-1-yl)acetic acid dissolves easily in water and dissolves to a lesser extent in ethanol.
Use in pharmaceuticals
Building block for synthesis This compound is used as a building block in the synthesis of various pharmaceuticals, such as antihistamines and antidepressants.
Importance for research
Valuable tool for drug development The structure and properties of 2-(piperazin-1-yl)acetic acid make it a valuable tool for researchers and scientists in the development of new drugs and therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 496808-05-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,6,8,0 and 8 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 496808-05:
(8*4)+(7*9)+(6*6)+(5*8)+(4*0)+(3*8)+(2*0)+(1*5)=200
200 % 10 = 0
So 496808-05-0 is a valid CAS Registry Number.
496808-05-0Relevant articles and documents
HETEROCYCLIC SPIRO-COMPOUNDS AS AM2 RECEPTOR INHIBITORS
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Page/Page column 148; 190, (2020/06/05)
Disclosed are compounds of the formula (I) and pharmaceutically acceptable salts thereof: wherein R1, R2, R4, R5, R6, R7, R8, R9, R10,Z, X1, X2, X3, L2, HET, n and q are as defined herein. The compounds are inhibitors of adrenomedullin receptor subtype 2 (AM2). Also disclosed are the compounds for use in the treatment of diseases modulated AM2, including proliferative diseases such as cancer; pharmaceutical compositions comprising the compounds; methods for preparing the compounds; and intermediates useful in the preparation of the compounds.